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folic acid antagonists

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson 0.01 sec.
folic acid antagonists
pl.n.
Modified pterins, such as aminopterin and amethopterin, that interfere with the action of folic acid and produce the symptoms of a folic acid deficiency.
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After studying the data, we concluded that first trimester exposure to folic acid antagonists is associated with increased risk for neural tube, cardiovascular and urinary tract defects," said principal investigator Dr.
Drugs that block folic acid in pregnancy double birth defects risk by Asian News International
When chemotherapy is required in early pregnancy, the physician may be able to minimize the additional risk of congenital malformation by avoiding combination therapy or use of folic acid antagonists such as methotrexate.
Abortion & Breast Cancer Hardest Case -- or Cruelest Myth? by Brind, Joel / National Right to Life News
FUSILEV is also indicated to diminish the toxicity and counteract the effects of impaired methotrexate elimination and of inadvertent overdosage of folic acid antagonists.
Spectrum Pharmaceuticals Announces That FDA Has Accepted FUSILEV[TM] ... by Business Wire
 
 
 
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