folate

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folate

 [fo´lāt]
the anionic form of folic acid.

fo·late

(fō'lāt),
A salt or ester of folic acid.

folate

/fo·late/ (fo´lāt)
1. the anionic form of folic acid.
2. more generally, any of a group of substances containing a form of pteroic acid conjugated with l-glutamic acid and having a variety of substitutions.

folate

(fō′lāt′)
n.
1. A salt or ester of folic acid.

folate

[fō′lāt]
1 a salt of folic acid.
2 any of a group of substances found in some foods and in mammalian cells that act as coenzymes and promote the chemical transfer of single carbon units from one molecule to another. See also folic acid.

folate

Any of the ionised forms of folic acid.

fo·late

(fō'lāt)
A salt or ester of folic acid.

folate (fōˑ·lāt),

n a B vitamin that is present in leafy green vegetables, dry peas and beans, and fortified breads and cereals. Folate deficiency may increase the risk of certain cancers, Alzheimer's disease, and certain birth defects, such as neural tube defects. Also used by some to enhance the effects of SSRI medications; to maintain cardiovascular health; to prevent tolerance of nitrates during nitrate therapy; and to treat gout, bipolar depression, osteoarthritis, osteoporosis, rheumatism, and vitiligo. Folate supplementation may be contraindicated for patients with seizure disorders and for those taking phenytoin. Also called
folic acid.

fo·late

(fō'lāt)
A salt or ester of folic acid.

folate (fō´lāt),

n a form of folic acid that helps transport single carbon units between molecules.

folate

the generic term for folic acid and related compounds.
References in periodicals archive ?
DSM, Parsippany, NJ, has partnered with Merck, Whitehouse Station, NJ, to distribute and market its L-MTITF Metafolin folate to the dietary supplement and food industries.
Kimmins said that fathers who eat high-fat, fast food diets or who are obese may not be able to use or metabolize folate in the same way as those with adequate levels of the vitamin.
Since folic acid fortification has become mandatory, the incidence of neural tube defects (NTDs) has declined in Canada by approximately 50%, (4) with improvements in blood folate indices (5,6) and folate intake.
Folate concentration in serum and erythrocytes is a marker of folate status, which is inversely associated with the plasma concentration of total homocysteine (tHcy).
Folate concentrations were quantified using reversed-phase high-performance liquid chromatography, and degradation products were identified using the same technique.
Merck Eprova AG is a wholly owned subsidiary of Merck KGaA, Darmstadt, Germany, and is the largest producer of specialty folates for oral and parenteral pharmaceutical applications and nutritional supplements.
Epidemiologist Martha Savaria Morris and four colleagues used data gathered on folks aged 15-39 years to examine associations between folate levels and history of depression.
Researchers are now exploiting cancer cells' craving for the water-soluble vitamin by harnessing folate as a therapeutic "Trojan Horse" to sneak cancer-fighting drugs directly into tumor cells.
Marginal folate deficiency is associated with an increased level of plasma homocysteine, an emerging risk factor for vascular diseases and stroke, and it also is linked to certain cancers, notably colon cancer.
Measurement of folates in serum and conventionally prepared whole blood lysates: application of an automated 96-well plate isotope-dilution tandem mass spectrometry method.
In humans, this particular compound is the predominant form of circulation and transport into the tissues, and it is the only folate that can cross the blood-brain barrier.