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folate |
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folate /fo·late/ (fo´lāt) 1. the anionic form of folic acid. 2. more generally, any of a group of substances containing a form of pteroic acid conjugated with l-glutamic acid and having a variety of substitutions.
folate [fō′lāt] 1 a salt of folic acid. 2 any of a group of substances found in some foods and in mammalian cells that act as coenzymes and promote the chemical transfer of single carbon units from one molecule to another. See also folic acid. folate (fōˑ·lāt), n a B vitamin that is present in leafy green vegetables, dry peas and beans, and fortified breads and cereals. Folate deficiency may increase the risk of certain cancers, Alzheimer's disease, and certain birth defects, such as neural tube defects. Also used by some to enhance the effects of SSRI medications; to maintain cardiovascular health; to prevent tolerance of nitrates during nitrate therapy; and to treat gout, bipolar depression, osteoarthritis, osteoporosis, rheumatism, and vitiligo. Folate supplementation may be contraindicated for patients with seizure disorders and for those taking phenytoin. Also called folic acid. folate (fō´lāt), n a form of folic acid that helps transport single carbon units between molecules. folate the generic term for folic acid and related compounds. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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The most likely explanation, these researchers say, "lies in the known increased bioavailability of folic acid ove r [natural] food folates. This is consistent with the established use of reduced folates for treatment of methanol/CHO toxicity. Vitamin B12 regulates one of two major cellular pathways for the production of folates, the cell's primary source of carbon and the progenitor for the synthesis of DNA. |
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