folate deficiency


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folate deficiency

a deficiency of folic acid. See also folic acid.

folate deficiency

Folic acid deficiency Hematology A condition caused by a decrease in dietary folic acid, resulting in megaloblastic anermia, GI tract complaints–eg, glossitis, stomatitis, malabsorption, infertility, neural tube defects, and possibly also psychiatric complaints and peripheral neuropathy. See Megaloblastic anemia.
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Some women with iron deficiency due to bariatric surgery or malabsorption also have vitamin B12 and, less commonly, folate deficiency, which can contribute to the development of anemia (see "Diagnosis of anemia, iron deficiency, and iron deficiency anemia in pregnancy.
Diagnosis and treatment of vitamin B12 and folate deficiency.
12] and folate deficiency and bone marrow disorders and normal in liver disease and alcohol use.
Macrocytosis is the earliest indication seen in complete blood counts of patients with vitamin B12 or folate deficiency.
4 However, previously there has been no detailed study in Pakistan of the biochemical etiology of this anemia, exploring the relative contributions of iron, vitamin B12 and folate deficiency.
The megaloblastic anemias are disorders caused by impaired DNAsynthesis usually due to vitamin B12 or folate deficiency.
If not received regularly, folate deficiency occurs in 2-3 months.
Those with a folate deficiency were found to be almost three-and-a-half times more likely to develop dementia.
According to the researchers, this threshold is higher than the standard cutoff for diagnosing folate deficiency (less than 10 nm/L).
Folate deficiency (serum folate 4 ng/mL or red blood cell folate < 151 ng/mL) and vitamin B12 deficiency (plasma vitamin B12 < 203 pg/mL) were obtained as a national prevalence.
Table 1: Prevalence of vitamin B12 and folate deficiency in children
B12 and folate deficiency was detected in 10% and 7% patients respectively.