focal segmental glomerulosclerosis

glomerulosclerosis /glo·mer·u·lo·scle·ro·sis/ (glo-mer″u-lo-sklĕ-ro´sis) fibrosis and scarring resulting in senescence of the renal glomeruli.

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diabetic glomerulosclerosis  intercapillary g.

focal segmental glomerulosclerosis  a syndrome of focal sclerosing lesions of the renal glomeruli with proteinuria, hematuria, hypertension, and nephrosis, with variable progression to end-stage renal disease.

intercapillary glomerulosclerosis  a degenerative complication of diabetes, manifested as albuminuria, nephrotic edema, hypertension, renal insufficiency, and retinopathy.

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focal segmental glomerulosclerosis

n.

Segmental collapse of glomerular capillaries with thickened basement membranes and increased mesangial matrix, seen sometimes in nephrotic syndrome or mesangial proliferative glomerulonephritis.

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glomerulosclerosis [glo-mer″u-lo-sklĕ-ro´sis]

arteriolar nephrosclerosis.

diabetic glomerulosclerosis (intercapillary glomerulosclerosis) a degenerative complication of diabetes mellitus in which there is glomerular mesangial expansion with either diffuse lesions or nodular (Kimmelstiel-Wilson) lesions; symptoms include albuminuria, nephrotic edema, hypertension, renal insufficiency, and retinopathy. The type with nodular lesions is also called Kimmelstiel-Wilson syndrome.

focal segmental glomerulosclerosis focal sclerosing lesions of the renal glomeruli, with proteinuria, hematuria, hypertension, and the nephrotic syndrome; it may be idiopathic or secondary to another condition. Called also focal glomerular sclerosis.