focal necrosis


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fo·cal ne·cro·sis

occurrence of numerous, relatively small or tiny, fairly well-circumscribed, usually spheroidal portions of tissue that manifest coagulative, caseous, or gummatous necrosis and are characteristically associated with agents that are hematogenously disseminated; frequently observed only in histologic sections, but the foci may be as large as 1-3 mm and macroscopically visible; arbitrarily, foci larger than that are usually not termed focal necrosis.

fo·cal ne·cro·sis

(fō'kăl nĕ-krō'sis)
Occurrence of numerous small, well-circumscribed zones of tissue that manifest coagulative, caseous, or gummatous necrosis.

focal necrosis

Necrosis in small scattered areas, often seen in infection.
See also: necrosis
References in periodicals archive ?
Minor or un noticed pressure due to vomiting, bending or coughing in addition to splenic congestion, infarction and focal necrosis leads to distension of the splenic capsule and rupture.
As one watches the artful collapsing of a tumor under the onslaught of the targeted genetic medicine, it is interesting to note that the complex mechanisms of cellular apoptosis, focal necrosis, and anti-angiogenesis were beautifully "translated" by a Native American artist/programmer by visualizing and digitizing time-lapse photography that revealed the collapsing of a pumpkin in a field.
The biopsy results revealed gelatinous degenerative change with focal necrosis (Figures 2 and 3).
The findings of percutaneous liver biopsy were consistent with drug-induced cholestatic hepatitis, revealing portal and lobular inflammatory infiltrates with excess of eosinophils, mild portal fibrosis, central and focal necrosis, and macrovesicular fatty infiltration (30%).
An analysis of items scored revealed a statistically significant decrease in piecemeal necrosis and improvements in focal necrosis, confluent necrosis, portal inflammation and fibrosis.
Liver autopsy specimens of terminal DSS patients generally showed massive or focal necrosis with little or no recruitment of polymorphonuclear cells or lymphocytes (3,4).