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focal glomerular sclerosis

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focal glomerular sclerosis,
focal sclerosing lesions of renal glomeruli with proteinuria, hematuria, hypertension, and the nephrotic syndrome. It may be idiopathic or secondary to other conditions, including heroin-abuse nephropathy, chronic interstitial nephritis, and malignancies. Exacerbations and remissions may occur, most often in children; progression to renal failure occurs at a variable and unpredictable rate. Also called focal glomerulosclerosis.


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A biopsy of his kidney shows he has focal glomerular sclerosis (hardening of the filtering apparatus in the kidney).
 
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