fluvastatin /flu·va·stat·in/ (floo´vah-stat″in) an inhibitor of cholesterol biosynthesis used as the sodium salt in the treatment of hyperlipidemia and to slow the progression of atherosclerosis associated with coronary heart disease.
fluvastatin,
fluvastatin
flu·va·stat·in (fl  v -st t n)n. A statin drug given to treat hyperlipidemia. |
fluvastatin,
an antilipidemic.
indications It is used as an adjunct treatment in primary hypercholesterolemia (types Ia and Ib) and in coronary atherosclerosis associated with coronary artery disease.
contraindications Factors that prohibit its use include known hypersensitivity to this drug, pregnancy, lactation, and active liver disease.
adverse effects Life-threatening effects are liver dysfunction, myositis, rhabdomyolysis, thrombocytopenia, hemolytic anemia, and leukopenia. Other adverse effects include rash, pruritus, nausea, constipation, diarrhea, dyspepsia, flatus, pancreatitis, lens opacities, myalgia, headache, dizziness, insomnia, fatigue, influenza, upper respiratory infection, rhinitis, cough, pharyngitis, and sinusitis.
fluvastatin
Lescol® Cardiology An HMG-CoA reductase inhibitor/statin that improves lipid profile of Pts with hypercholesterolemia and mixed dyslipidemia Effect Slowing coronary ASHD in CAD by ↓ total-C, LDL-C, ↑
HDL-C, ↓ TGs Adverse events Rash. See LDL-C, Hypercholesterolemia, Statin.
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