fluvastatin


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Related to fluvastatin: Fluvastatin sodium

fluvastatin

 [floo´vah-stat″in]
an inhibitor of cholesterol biosynthesis used as the sodium salt in the treatment of hyperlipidemia and to slow the progression of atherosclerosis associated with coronary heart disease.

fluvastatin

/flu·va·stat·in/ (floo´vah-stat″in) an inhibitor of cholesterol biosynthesis used as the sodium salt in the treatment of hyperlipidemia and to slow the progression of atherosclerosis associated with coronary heart disease.

fluvastatin

(flo͞o′və-stăt′n)
n.
A statin, C24H26FNO4, used in the form of its sodium salt, that blocks the body's synthesis of cholesterol and is administered especially to individuals who are at risk for heart disease.

fluvastatin

an antilipidemic.
indications It is used as an adjunct treatment in primary hypercholesterolemia (types Ia and Ib) and in coronary atherosclerosis associated with coronary artery disease.
contraindications Factors that prohibit its use include known hypersensitivity to this drug, pregnancy, lactation, and active liver disease.
adverse effects Life-threatening effects are liver dysfunction, myositis, rhabdomyolysis, thrombocytopenia, hemolytic anemia, and leukopenia. Other adverse effects include rash, pruritus, nausea, constipation, diarrhea, dyspepsia, flatus, pancreatitis, lens opacities, myalgia, headache, dizziness, insomnia, fatigue, influenza, upper respiratory infection, rhinitis, cough, pharyngitis, and sinusitis.

fluvastatin

Lescol® Cardiology An HMG-CoA reductase inhibitor/statin that improves lipid profile of Pts with hypercholesterolemia and mixed dyslipidemia Effect Slowing coronary ASHD in CAD by ↓ total-C, LDL-C, ↑ HDL-C, ↓ TGs Adverse events Rash. See LDL-C, Hypercholesterolemia, Statin.

fluvastatin

A statin drug (see STATINS) that blocks the synthesis of cholesterol in the body and can be used to lower unduly high blood cholesterol levels. A brand name is Lescol.
References in periodicals archive ?
The problem is that fluvastatin is about equal to giving jelly beans" for lipid control.
Fluvastatin is primarily metabolized by 2C9, whereas pravastatin and rosuvastatin are eliminated unchanged by the liver and kidney (21).
Tendon manifestations were related to atorvastatin, simvastatin, pravastatin, fluvastatin, and rosuvastatin.
The marketshares of other products, such as fluvastatin, lovastatin, rosuvastatin, and ezetimibe/simvastatin, were not reported, because they accounted for less than 15% of prescriptions in this period.
Fluvastatin improves endothelial dysfunction in overweight postmenopausal women through small dense low-density lipoprotein reduction.
Similarly, when pravastatin, simvastatin, atorvastatin, cerivastatin, fluvastatin, and lovastatin were considered individually, none of the agents reduced the risk of cancer or cancer death.
Nice looked at five statins currently licensed in the UK - ator-vastatin, fluvastatin, pravastatin, rosuvastatin and simvastatin.
Now underway is a pilot biomarker study at the University of California, San Francisco, Dana-Farber Cancer Institute in Boston, Memorial Sloan-Kettering Cancer Center in New York, and the University of Chicago, where women with newly diagnosed ductal carcinoma in situ or stage I invasive breast cancer by core biopsy are being randomized to 3-6 weeks of fluvastatin at either 20 or 80 mg/day before undergoing definitive surgery.
Researchers at the National Hospital in Oslo, Norway, led by Hallvard Holdaas, analyzed the effects of fluvastatin in 2,102 kidney transplant recipients and found it was highly effective in reducing the patients' level of low-density lipoprotein (LDL) cholesterol (the "bad cholesterol").
12) Statins Atorvastatin (Lipitor), Lowers high blood fluvastatin (Lescol), cholesterol levels lovastatin (Mevacor), by reducing LDL pravastatin (Pravachol), ("bad") cholesterol simvastatin (Zocor) and levels; helps to rosuvastatin (Crestor) increase HDL ("good") cholesterol and reduce triglyceride levels.
His current medication regimen included quinapril, digoxin, fluvastatin, atorvastatin, amoxicillin, and prednisone.
Lipid-lowering drugs such as atorvastatin (Lipitor), pravastatin (Pravachol) or fluvastatin (Lescol) should be used with caution when combined with saquinavir.