fluoxymesterone


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fluoxymesterone

 [floo-ok″se-mes´ter-ōn]
an androgen used in the treatment of male hypogonadism and delayed male puberty and in palliation of metastatic breast carcinoma in postmenopausal women; administered orally.

fluoxymesterone

/flu·ox·y·mes·ter·one/ (floo-ok″se-mes´ter-ōn) an androgen used in the treatment of male hypogonadism and delayed male puberty and in palliation of metastatic breast carcinoma in postmenopausal women.

fluoxymesterone

[flo̅o̅·ok′simes′tərōn]
an androgenic and anabolic steroid.
indications It is prescribed in the treatment of testosterone deficiency, breast cancer in females, and delayed puberty in males.
contraindications Male breast or prostate cancer, liver disease, known or suspected pregnancy, or known hypersensitivity to this drug prohibits its use.
adverse effects It commonly causes priapism in males, menstrual irregularities in females, edema, and acne. Among the more serious adverse effects are anaphylaxis, hypercalcemia, and jaundice.

fluoxymesterone

Endocrinology A 17α-alkylated derivative of testosterone used for androgen replacement therapy Pros Oral Cons Hepatotoxicity–cholestasis, peliosis hepatis, liver tumors. See Androgen replacement therapy.

fluoxymesterone

(flŏŏok´sēmes´tərōn´),
n brand names: Android-F, Halotestin;
drug class: androgenic anabolic steroid, Controlled Substance Schedule III;
action: increases weight by building body tissue; increases potassium, phosphorus, chloride, nitrogen levels; increases bone development;
uses: impotence from testicular deficiency, hypogonadism, breast engorgement, palliative treatment of female breast cancer.

fluoxymesterone

an anabolic androgenic steroid.
References in periodicals archive ?
As the sole supplier of Fluoxymesterone Tablets in the U.
Exogenous: 1-androstendiol, 1-androstendione, bolandiol, bolasterone, boldenone, boldione, calusterone, clostebol, danazol, dehydrochlormethyltestosterone, desoxymethyltestosterone, drostanolone, ethylestrenol, fluoxymesterone, formebolone, furazabol, gestrinone, 4-hydroxytestosterone, mestanolone, mesterolone, metenolone, methandienone, methandriol, methasterone, methyldienolone, methyl-1-testosterone, methylnortestosterone, methyltrienolone, methyltestosterone, mibolerone, nandrolone, 19-norandrostenedione, norboletone, norclostebol, norethandrolone, oxabolone, oxandrolone, oxymesterone, oxymetholone, prostanozol, quinbolone, tanozolol, stenbolone, 1-testosterone, tetrahydrogestrinone, trenbolone
Those substances on the list are Fluoxymesterone, Nandrolone (e.
The first evidence linking CYP2D6 variants with treatment response was obtained from a prospective randomized phase III trial of postmenopausal women with ER-positive breast cancer (North Central Cancer Treatment Group adjuvant breast cancer trial) for the investigation of the effect of adding the androgen fluoxymesterone for 1 year to the standard regimen of 5 years of adjuvant tamoxifen.
The anti-tumour activity of fluoxymesterone appears related to reduction or competitive inhibition of prolactin receptors or estrogen receptors [21,5].
Fluoxymesterone (CAS: 76-43-7), hoechst 33258, mitomycin C and cyclophosphamide were procured from Sigma.
The prognostic efficacy of the tests was assessed through the use of archived tumor specimens collected from 122 women who participated in a tamoxifen treatment study that was done in the United States during the 1990s; the goal of that study was to compare adjuvant treatment with tamoxifen alone to treatment with tamoxifen plus fluoxymesterone.
The next step assessed the prognostic power of both ratios through the use of the tumor specimens taken from the 122 women who had participated in the tamoxifen and fluoxymesterone study.
PRODUCT DERIVATIVE Anadiol Testosterone Anadrol 50 Oxymetholone Anavar Oxandrolone Cheque Drops Mibolerone Deca-Durabolin Nandrolone Depo-Testosterone Testosterone Dianabol Methandrostenolone Equipoise Boldenone Finaject Trenobolone Lyphomed Nandrolone Malogen Testosterone Nandrabolin Nandrolone Parabolan Trenbolone Primobolan Methenolone Primoteston Depot Testosterone Sostenon 250 Testosterone (Esters) Sten Testosterone Stenox Fluoxymesterone Winstrol V Stanozolol
In a series of comprehensive pre-clinical studies carried out in established animal models, LGD2226 dosed once daily in long-term studies was able to fully maintain muscle and bone mass at doses much lower than those of a comparator, fluoxymesterone, an orally active steroidal androgen.
Current androgen therapies include testosterone, in injectible or transdermal delivery forms that limit its use and range of therapeutic applications, and oral steroidal androgens, such as fluoxymesterone.
Metabolism of anabolic steroids in humans: synthesis of 6[beta]-hydroxymetabolites of 4-chloro-1,2-dehydro-17[alpha]-methyltestosterone, fluoxymesterone, and metandienone.