fluorescein


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fluorescein

 [floo͡-res´ēn]
a fluorescing dye; the sodium salt is used as a contrast medium in retinal angiography and as a diagnostic aid for revealing corneal lesions and fitting contact lenses.

fluor·es·ce·in

(flōr-es'ē-in), [C.I. 45350]
An orange-red crystalline powder that yields a bright green fluorescence in solution and is reduced to fluorescin; a nontoxic, water-soluble indicator used diagnostically to trace water flow.

fluorescein

/flu·o·res·ce·in/ (fldbobr-res´ēn) a fluorescing dye; its sodium salt is used as a tracer in retinal angiography and as a diagnostic aid for revealing corneal trauma and fitting contact lenses.

fluorescein

(flo͝o-rĕs′ē-ĭn, flô-, flō-)
n.
An orange-red compound, C20H12O5, that exhibits intense fluorescence in alkaline solution and is used in medicine for diagnostic purposes, in oceanography as a tracer, and as a textile dye.

fluor·es·ce·in

(flōr-es'ē-in)
[C.I. 45350] An orange-red crystalline powder that yields a bright green fluorescence in solution, and is reduced to fluorescin; a nontoxic, water-soluble indicator used diagnostically to trace water flow and to visualize corneal abrasions or ulcers.

fluorescein

A green dye that fluoresces bright yellow in blue or ultraviolet light. It is used to tag (label) and thus show up ANTIBODIES in tissues. It is also much used by eye specialists (ophthalmologists) to show up ulcers on the cornea and to delineate for photography the blood vessels of the retina. For the latter purpose, the due is injected rapidly into the bloodstream (fluorescein angiography). The drug is on the WHO official list. Brand names are fluorescein, Minims fluorescein, Minims lignocaine (lidocaine, a local anaesthetic) and fluorescein, and Minims proxymetacaine (a local anaesthetic) and fluorescein.

Fluorescein

A brand name for FLUORESCEIN.

Fluorescein

A fluorescent chemical used to examine the cornea.
Mentioned in: Corneal Ulcers

fluorescein

A fluorescent, weak dibasic acid with a molecular weight of 376 whose sodium salt is used in dilute solution as a dye in the fitting of contact lenses, in the detection of corneal abrasions, etc. It is a yellowish-red compound, which fluoresces a brilliant yellow-green under ultraviolet or blue illumination (Fig. F7). Syn. sodium fluorescein. See fluorexon; Burton lamp; Wood's light; rose bengal; staining; break-up time test; fluorescein test.
Fig. F7 Fluorescein on the corneal surface staining A, an abraded area, and B, some damaged epithelial cellsenlarge picture
Fig. F7 Fluorescein on the corneal surface staining A, an abraded area, and B, some damaged epithelial cells

fluor·es·ce·in

(flōr-es'ē-in)
Nontoxic, water-soluble indicator used diagnostically to trace water flow and visualize corneal abrasions.

fluorescein (flôres´ēin),

n in dentistry, a dye applied to teeth to reveal plaque. In ophthalmology, it is used to discover corneal lesions.

fluorescein

a fluorescing dye, an acid fluorochrome; the sodium salt is used in solution to reveal corneal lesions and as a test of circulation in the retina and extremities. The isothiocyanate derivative (FITC) is used for labeling of immunoglobulins in various immunofluorescence techniques.

fluorescein strips
sterilized applicators impregnated with fluorescein for use in ophthalmic tests.
References in periodicals archive ?
The fluorescein angiography, however, had not been performed with such purpose, until this study was developed.
Interference of fluorescein, used in retinal angiography, with certain clinical laboratory tests.
In order to identify the possible involvement of MCT in the observed pharmacokinetic interaction, Caco-2 cells were used for transport study employing fluorescein as a typical substrate of MCI mn assay showed that incubation of HQT, SR, PR, GR and JF at the concentration of 2.
Next, they added a solution of captopril with various concentrations to phosphate buffer of gold nanoparticles - fluorescein isothiocyanate, and they studied the fluorescent spectrum of its emitted fluorescein isothiocyanate.
Fluorescein angiography was performed on 2 occasions, approximately 48 hours apart.
Fluorescein angiography showed immediate and dramatic restoration in flow past the obstructed arteriole in all patients.
Fluorescein identified gangrenous bowel in 3 additional patients.
The only CLE-specific complications--five cases of nausea and nine cases of decreased blood pressure--were related to the intravenous fluorescein.
It tends to be a subtler test than the fluorescein stain, picking up lighter areas of dryness on the eye.
Infected cells that showed CPEs were harvested and evaluated by immunofluorescent assay (IFA) (3) for flavivirus antigen, by using fluorescein isothiocyanate-labeled flavivirus polyclonal antisera (Centers for Disease Control and Prevention, Puerto Rico), and for WNV antigen by using the WNV-specific monoclonal immunoglobulin M (IgM) antibody H5-46 and IgG neutralizing monoclonal antibody 7H2.