flunitrazepam


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Related to flunitrazepam: gamma hydroxybutyrate

flu·ni·traz·e·pam

(flū'nī-trāz'ĕ-pam),
A benzodiazepine compound with sedative and hypnotic properties.

Flunitrazepam, said to be the most widely prescribed sedative and hypnotic in Europe, although it is not licensed for sale in the U.S., has been the subject of increasing concern as illegal distribution and abuse of the drug have spread from southern U.S. states to other parts of this country. Abuse is particularly prevalent among high school and college youth. Used alone, flunitrazepam induces mild euphoria and sedation. It is often taken with other agents, for example to enhance a heroin high or to ease the experience of coming down from a cocaine or crack high. Flunitrazepam and alcohol have a synergistic effect, producing disinhibition and amnesia when taken together. For this reason the drug may be surreptitiously added to alcoholic drinks to facilitate date rape. Part of the popularity of the drug arises from its low cost and the availability of legally manufactured pure tablets. Flunitrazepam is marketed by Hoffman-La Roche under the brand name Rohypnol. Street names include "circles," "Mexican Valium," "la rocha," "R2," "rib," "roaches," "roachies," "Roche," "roofenol," "roofies," "rope," "rophies," and "ruffies." Being under the influence of the drug is referred to as being "roached out." The effects of flunitrazepam begin within 30 minutes after ingestion, peak within 2 hours, and may persist for 8 hours or more. Adverse effects include drowsiness, confusion, amnesia, paradoxic excitement or aggressiveness, visual disturbances, hypotension, gastrointestinal upset, and urinary retention. Lethal overdose is uncommon. Continued use results in physical dependence. Withdrawal symptoms range from headache, muscle pain, restlessness, and confusion to loss of identity, hallucinations, delirium, convulsions, and cardiovascular collapse. Withdrawal seizures can occur a week or more after cessation of use. Phenobarbital has been used to ease medically supervised withdrawal. Tablets of Rohypnol currently produced by Hoffman-LaRoche dissolve slowly in beverages and release a bright blue color so as to render covert administration less feasible.

flunitrazepam

(flo͞o′nĭ-trăz′ə-păm)
n.
A powerful sedative drug, C16H12FN3O3, that is illegal in the United States but is used elsewhere as a hypnotic and in anesthesia. It is popularly known as a "date rape" drug because it can cause semiconsciousness and memory blackouts and has been used in committing sexual assault.
A benzodiazepine that is ± 10-fold more potent than Valium Route of administration Oral, pulverised/snorted
Effects Slurred speech, impaired judgement, difficulty walking, sedation, blackouts of up to 24 hours, amnesia, respiratory distress; may have paradoxic effects and trigger aggression. Overdose or death can occur if mixed with other drugs or alcohol.
It is popularly known as the ‘date-rape’ drug.
In Texas, to be under the Influence of Rohypnol is 'To Get Roached’.

flunitrazepam

Rohypnol Pharmacology A benzodiazepine which has acquired notoriety by its slang name, the date rape drug, see there.

flunitrazepam

A BENZODIAZEPINE drug of moderate length of action used for short periods to treat insomnia. A brand name is Rohypnol. The drug has acquired notoriety because of the frequency with which it has been added illegally to alcoholic drinks as an aid to rape.
References in periodicals archive ?
for flunitrazepam and 7-amino-flunitrazepam by GC/ MS-NCI; Forensic Sci
5 Diazepam 10 Flunitrazepam 1 Flurazepam 15-30 Loprazolam 1 Lorazepam 1 Lormetazepam 1 Nitrazepam 10 Oxazepam 20 Temazepam 20 (a) Clinical potency for hypnotic or anxiolytic effects may vary between individuals; equivalent doses are approximate.
Durante a fase de coleta de dados, fazia uso diario dos seguintes medicamentos: fenitoina 100 mg; clonazepan 20 mg; haloperidol, 5 mg; cloridrato de clorpromazina 100 mg; flunitrazepam 1 mg; polivitaminico (buclizina + cafeina + lisina + complexo B) 1 g.
Flunitrazepam has had a long history of abuse by heroin and cocaine addicts.
Notwithstanding any penalty provided in this subsection, any person convicted under this subsection for the possession of flunitrazepam shall be imprisoned for not more than 3 years, shall be fined as otherwise provided in this section, or both.
Ions of Interest Oxycodone hydroxyl-imino tri-methyl Oxymorphone hydroxyl-imino silyl derivatives tri-methyl silyl derivatives Principal ions OCOD Principal ions OMOR 459 analyte (common ion) 459 analyte (common ion) 474 analyts 533 analyte 465 d6 analog 462 d3 analog 480 analog 536 d3 analog 1 Amphetamine 2 Phentermine 3 Methamphetamine 4 Nicotine 5 Methylenedioxyamphetamine(MDA) 6 Methylenedioxymethamphetamine(MDMA) 7 Methylenedioxyethylamphetamine 8 Meperidine 9 Phencyclidine 10 Methadone 11 Cocaine 12 SKF-525a (RTL Compound) 13 Oxazepam 14 Tetrahydrocannabinol 15 Codeine 16 Lorazepam 17 Diazepam 18 Hydrocodone 19 Oxycodone 20 Temazepam 21 Diacetylmorphine 22 Flunitrazepam 23 Nitrazepam 24 Clonazepam 25 Alprazolam 26 Verapamil 27 Strychnine 28 Trazodone
Apigenin, one of the predominant flavonoids in chamomile, was found to competitively inhibit the binding of flunitrazepam (a benzodiazepine receptor blocker of).
Do zopiclone, zolpidem and flunitrazepam have residual effects on simulated task of collision anticipation?
A different study showed that pretreatment with flunitrazepam (the benzodiazepine most often associated with deaths in Europe) significantly increased the lethality of methadone and buprenorphine (Borron et al.
In January, February and March, the last months for which figures for the entire force area are available, officers took 58 batches of Valium, also known as diazepam, along with nitrazepam, another drug from the Valium family and flunitrazepam, a powerful tranquilliser better known as the date-rape drug Rohypnol, off the streets.
5 mg versus flunitrazepam 1 mg and placebo on driving performance and ocular saccades.
Otras benzodiacepinas que se han utilizado para sedacion son el lorazepam y el flunitrazepam pero existe poca bibliografia sobre su uso en esta indicacion.