fluid challenge

Also found in: Dictionary, Thesaurus, Legal, Encyclopedia.

fluid challenge

The rapid infusion of fluids (crystalloids such as normal saline, or colloids, such as albumin) to resuscitate blood pressure in a patient thought to be hypovolemic.

Patient care

In a typical child 20 mL/kg of normal saline is given intravenously (or intraosseously) over 30 min. The volume infused into an adult is usually 250–1000 mL. The lower volume is used if there are concerns that the patient may develop pulmonary edema. The patient's blood pressure, heart rate and rhythm, oxygenation, and respirations are closely monitored during and after the infusion for evidence of a positive response, e.g., a mean arterial pressure that rises above 70 mm Hg, or deterioration, e.g., increasing dyspnea, ventricular ectopy, or hypoxia. Patients who respond favorably to a fluid challenge are typically placed on a maintenance infusion of fluids to sustain them hemodynamically.

See also: challenge
References in periodicals archive ?
Fluid responsiveness was defined as a ≥15% increase in CO after fluid challenge when compared with baseline CO.
Of the 42 patients, 19 (45%) responded to fluid challenge, whereas 23 (55%) did not.
7 %) of the mini fluid challenges defined as non-responders.
This retrospective observational study used the ROC curve and gray zone approaches to examine the accuracy of cPDE in the evaluation of hemodilution response to mini fluid challenges with crystalloids in the mVLT protocol.
i] is the plasma dilution efficacy of the fluid challenge number i, [PD.
i] is arterio-capillary plasma dilution efficacy difference of the fluid challenge number i, a[PDE.
Four out of five patients with FTc less than 350 ms in our study responded to fluid challenge, while all participants with FTc greater than 350 ms were non-responders.
These variables are clinically meaningful endpoints against which to define the clinical response to fluid challenge (fluid responsiveness).
Can changes in arterial pressure be used to detect changes in cardiac index during fluid challenge in patients with septic shock?
where acGAP--arterio-capillary gap, aHb--arterial Hb, and SpHb--capillary Hb; i--identification number of an individual in the pool, 1--data point after first mini fluid challenge, b-baseline.
Maternal hemodynamic parameters, including SBP, mean BP (MBP), HR, SpO [sub]2 , CO and SV, were recorded at the baseline (T1), following coloading with LR of 10 ml/kg (T2), 4 min following LR coloading (following first fluid challenge test) (T3), 8 min following LR coloading (following second fluid challenge test) (T4), stable blockade level obtained (thoracic level 5-3) (T5), immediate after delivery (T6), placental expulsion (T7), and discharge from operating room (T8).
Treatment for septic shock was standardized,[sup][4] including vasopressors (norepinephrine with epinephrine as a rescue therapy) to MAP, in addition to repeated fluid challenges with crystalloids, natural albumin, and artificial colloids (hydroxyethyl starch solutions) to achieve a CVP of 8–12 mmHg, to maintain a MAP of at least 65 mmHg and to ensure that the urine output was at least 0.