flucloxacillin


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flucloxacillin

A semisynthetic PENICILLIN antibiotic, readily absorbed when taken by mouth and effective against organisms that produce penicillin-destroying enzymes (beta-lactamases). A brand name is Floxapen. Formulated with ampicillin it is marketed as Magnapen.

flucloxacillin

; Floxapen systemic antibiotic used in the treatment of beta-lactamase-producing staphylococcal infections, e.g. impetigo, cellulitis and osteomyelitis; adult dose = 250-500 mg dose every 6 hours at least 30 minutes before food (child dose = half adult dose)

flucloxacillin

a penicillinase-resistant antibiotic; an isoxazolyl derivative of penicillin.
References in periodicals archive ?
049 Amoxicillin 13/82 (16) 5/52 (10) NS Amoxicillin/ 3/82 (4) 4/52 (8) NS clavulanic acid Piperacillin/ 1/82 (1) 5/52 (10) NS tazobactam Cephalosporin 14/82 (17) 17/52 (33) NS Co-trimoxazole 0/82 (0) 1/52 (2) NS Flucloxacillin 2/82 (2) 0/52 (0) NS Clarithromycin 0/82 (0) 1/52 (2) NS No treatment 1/82 (1) 1/52 (2) NS Unknown 0/82 (0) 1/52 (2) NS Patients with 34/74 (46) NA NA adequate treatment ([double dagger]) * NS, not significant; NA, not applicable.
Protein binding of <70% is usually of little clinical consequence, but commonly used antibiotics such as ertapenem, teicoplanin, ceftriaxone, flucloxacillin and daptomycin are highly protein bound (>80% protein binding).
penicillin and amoxicillin); whereas the presence of mecA expands resistance to also include flucloxacillin, [beta]-lactamase inhibitor combinations (e.
For example, ampicillin, amoxicillin and flucloxacillin are one group of antibiotics.
Similarly, treatment failure rates for commonly prescribed antibiotics such as amoxicillin, penicillin and flucloxacillin remained below 20% throughout the period.
Flucloxacillin 1 g 4 times a day was started and 16 days of treatment were completed.
2004) that modulation of beta-lactam resistance by (-)-epicatechin gallate (ECG) significantly enhanced the activities of flucloxacillin and the carbapenem antibiotics imipenem and meropenem against 40 MRSA isolates, while both (-)-epicatechin and H-epicatechin-3-cyclohexylcarboxylate were unable to reverse resistance to oxacillin.
A review of the operative wound 1 week post-operatively showed a mildly inflamed medial wound which was treated with oral flucloxacillin (250 mg QDS) for 1 week.
Miss Leighton said she was unable to comment on her admission, heard by the Nursing and Midwifery Council last week, of stealing drugs including an antibiotic named flucloxacillin, a box of ibuprofen and some tramadol tablets from Stepping Hill Hospital.
Staphylococcus aureus was isolated from a pus swab of the sternal lesion and treated with a course of flucloxacillin.
Continuous infusions were used in only four patients involving vancomycin, meropenem, benzylpenicillin and flucloxacillin.
Postoperatively, she received intravenous flucloxacillin and oral fusidic acid for 1 week and orally for 5 weeks.