flosequinan


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flosequinan

Cardiology A quinolone that improves heart mechanics; it was withdrawn from the market when it was linked to ↑ mortality. See FACET, REFLECT.
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Called the Prospective Randomized Flosequinan Longevity Evaluation (PROFILE), the mortality study began in 1991.
Kurtz said the convenient once-a-day dosing of MANOPLAX is possible because flosequinan is rapidly and extensively absorbed and then converted by the liver to a longer-acting sulfone metabolite.