flipped LDH

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flipped LDH

Cardiology An inversion of the ratio of LD isoenzymes LD₁ and LD₂; LD₁ is a tetramer of 4 H–heart subunits, and is the predominant cardiac LD isoenzyme; it migrates more rapidly at pH of 8.6 than LD₅, normally the LD₁ peak is less than that of the LD₂, a ratio that is inverted–flipped in 80% of MIs within the first 48 hrs DiffDx LD flips also occur in renal infarcts, hemolysis, hypothyroidism, and gastric CA

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