flipped LDH

flipped LDH

Cardiology An inversion of the ratio of LD isoenzymes LD1 and LD2; LD1 is a tetramer of 4 H–heart subunits, and is the predominant cardiac LD isoenzyme; it migrates more rapidly at pH of 8.6 than LD5, normally the LD1 peak is less than that of the LD2, a ratio that is inverted–flipped in 80% of MIs within the first 48 hrs DiffDx LD flips also occur in renal infarcts, hemolysis, hypothyroidism, and gastric CA