bisacodyl

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Related to fleet: Fleet Laxative

bisacodyl

 [bis-ak´o-dil]
a contact laxative used before procedures involving the colon; administered orally or by rectal suppository, either as the base or as a complex with tannic acid (bisacodyl tannex).

bisacodyl

Alophen, Apo-bisacodyl (CA), Biolax (UK), Bisac-Evac, Biscolax, Carter's Little Pills (CA), Correctol, Dacodyl, Doxidan, Dulcolax, Ex-Lax Ultra, Femilax, Fleet Bisacodyl, Fleet Stimulant Laxative, Gentlax (CA), Laxoberal (UK), Veracolate

Pharmacologic class: Stimulant laxative

Therapeutic class: Laxative

Pregnancy risk category B

Action

Unclear. Thought to stimulate colonic mucosa, producing parasympathetic reflexes that enhance peristalsis and increase water and electrolyte secretion, thereby causing evacuation of colon.

Availability

Enema: 0.33 mg/ml, 10 mg/ml

Powder for rectal solution: 1.5 mg bisacodyl and 2.5 g tannic acid

Suppositories (rectal): 5 mg, 10 mg

Tablets (enteric-coated): 5 mg

Indications and dosages

Constipation; bowel cleansing for childbirth, surgery, and endoscopic examination

Adults and children ages 12 and older: 5 to 15 mg P.O. or 10 mg P.R. as a single dose

Children older than age 3: 5 to 10 mg or 0.3 mg/kg P.O. as a single dose

Children ages 2 and older: 5 to 10 mg P.R. as a single dose

Children younger than age 2: 5 mg P.R. as a single dose

Contraindications

• Hypersensitivity to drug
• Intestinal obstruction
• Gastroenteritis
• Appendicitis

Precautions

Use cautiously in:
• hypersensitivity to tannic acid
• severe cardiovascular disease, anal or rectal fissures
• pregnant or breastfeeding patients.

Administration

• Make sure patient swallows tablets whole without chewing.
• Don't give tablets within 1 hour of dairy products or antacids (may break down enteric coating).
• Know that drug should be used only for short periods.

Adverse reactions

CNS: dizziness, syncope

GI: nausea, vomiting, diarrhea (with high doses), abdominal pain, burning sensation in rectum (with suppositories), laxative dependence, protein-losing enteropathy

Metabolic: hypokalemia, fluid and electrolyte imbalances, tetany, alkalosis

Musculoskeletal: muscle weakness (with excessive use)

Interactions

Drug-drug.Antacids: gastric irritation, dyspepsia

Drug-diagnostic tests.Calcium, magnesium, potassium: decreased levels

Phosphate, sodium: increased levels

Drug-food.Dairy products: gastric irritation

Patient monitoring

• Assess stools for frequency and consistency.
• Monitor patient for electrolyte imbalances and dehydration.

Patient teaching

• Instruct patient to swallow (not chew) enteric-coated tablets no sooner than 1 hour before or after ingesting antacids or dairy products. Tell him not to chew tablets.
• Advise patient not to use bisacodyl or other laxatives habitually because this may lead to laxative dependence.
• Suggest other ways to prevent constipation, such as by eating more fruits, vegetables, and whole grains to increase dietary bulk and by drinking 8 to 10 glasses of water daily.
• As appropriate, review all other significant and life-threatening adverse reactions and interactions, especially those related to the drugs, tests, and foods mentioned above.

bisacodyl

/bis·ac·o·dyl/ (bis-ak´ah-dil) (bis″ah-ko´dil) a contact laxative, used as the base or as a complex with tannic acid (b. tannex) .

bisacodyl

(bĭs-ăk′ə-dĭl, bĭs′ə-kō′dĭl)
n.
An over-the-counter laxative taken by mouth or per rectum to treat constipation.

bisacodyl

[bisak′ōdil]
a cathartic.
indications It is prescribed in the treatment of acute or chronic constipation or for emptying of the bowel before or after surgery or before diagnostic radiographic procedures.
contraindications Abdominal pain, nausea, vomiting, rectal fissures, ulcerated hemorrhoids, or known hypersensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse reactions are colic, abdominal pain, and diarrhea.

bisacodyl

A laxative used to manage constipation, especially in the elderly, as well as neurogenic bowel dysfunction.

Mechanism
Enteric nerve stimulation, increases fluid and salt secretion.

bisacodyl

Dulcolax An agent used to manage constipation

bisacodyl

A drug used in the treatment of constipation. A brand name is Dulco-Lax.

bisacodyl (bisak´ədil),

n brand names: Dulcolax, Fleet Bisacodyl, Bisacodyl Uniserts, Fleet Laxative;
drug class: laxative, stimulant;
ac-tion: acts directly on intestine by increasing motor activity;
uses: short-term treatment of constipation, and bowel or rectal preparation for surgery or examination.

bisacodyl

a diphenylmethane stimulant cathartic.
References in classic literature ?
Prothous, fleet of foot, was their leader, and with him there came forty ships.
They were driven by Eumelus, and were as fleet as birds.
Guess it's the fust time her skipper ever met up with the Fleet this way.
The ship was moving slowly at the time, and as I lunged overboard into the darkness beneath I shuddered at the awful plunge I thought awaited me, for all day the fleet had sailed thousands of feet above the ground; but to my utter surprise I struck upon a soft mass of vegetation not twenty feet from the deck of the ship.
Out went the lights; the fleet became dim, dark bulks against an intense blue sky that still retained an occasional star.
And now two great fleets were moving upon Helium, while the Dusarian spies at the court of Tardos Mors saw to it that the twin cities remained in ignorance of their danger.
And while we were suffering all these disappoint-ments Hooja's fleet appeared in the distance!
Our faces were unfamiliar on the Lower Bay, but as the Reindeer was well known as a fish-patrol sloop, the Greek boy, whose name was Nicholas, and I were to sail some innocent-looking craft down to Asparagus Island and join the oyster pirates' fleet.
The fleets of all the world were there, and day and night millions of tons of battleships ploughed the brine of her coasts, and nothing happened.
In the beginning of the fight one little store ship of the English fleet hovered near.
It was indispensable to most public conveniences in those days, that they should be public nuisances likewise; and Fleet Market maintained the principle to admiration.
Are fleets and armies and revenues necessary to this purpose?