fixed-dose combination

fixed-dose combination

fixed-dose combination

A combination of two or more drugs in one capsule, injection, or tablet to simplify drug regimens and improve compliance.
References in periodicals archive ?
Ledipasvir + Sofosbuvir is a two drug fixed-dose combination product that include 90 mg of ledipasvir and 400 mg of sofosbuvir in a single tablet, and sold internationally by Gilead Sciences Inc.
We are initiating a Phase 1b safety and pharmacokinetics trial for our candidate otoprotectant formulation, an oral, fixed-dose combination of two antioxidant molecules HPN-07 plus n-acetylcysteine (NAC).
The approval makes it the first fixed-dose combination HIV drug approved before its individual novel components.
He raised suspicions about the efficacy of fixed-dose combination anti-retroviral drugs produced by generic manufacturers.
AIDS Treatment News: Recently the FDA approved two once-a-day fixed-dose combination pills--Epzicom (Ziagen plus Epivir) from GlaxoSmithKline, and Truvada (Viread plus Emtriva) from Gilead Sciences.
US DHHS announces expedited review process by the FDA for fixed-dose combination and co-packaged products to be used by the US in purchasing medications under PEPFAR.
Murray Lumpkin, the FDA's deputy commissioner for international and special programs, said that the FDA is "extremely hopeful" that the fixed-dose combination pill will be particularly helpful for the HIV-infected population in the developing world.
The Drugs for Neglected Diseases Initiative in March announced that ASAQ, a fixed-dose combination of artesunate and amodiaquine, will soon be available throughout the area where the majority of the deadly malaria cases hit.
David Nash reviews the rationale for combination therapy in treating hypertension, focusing on the fixed-dose combination of an ARB and thiazide-type diuretic.
Emtricitabine is marketed by Gilead under the brand name Emtriva, and a fixed-dose combination of Emtricitabine and Tenofovir Disoproxil Fumarate is made available under the brand name Truvada.
Schering-Plough Corporation (Kenilworth, NJ) announced changes to its global collaboration with Novartis for the development and commercialization of fixed-dose combination therapies for the treatment of asthma and chronic obstructive pulmonary disease (COPD).