first-line treatment


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first-line treatment

The initial, preferred, or best treatment for a disease. It is often the therapy that combines the best efficacy with the best safety profile and/or the lowest cost.
Synonym: first-line therapy
References in periodicals archive ?
According to the report, individuals with chronic pain, epilepsy, Parkinson's disease, and depression prefer first-line treatment options such as meditation, physiotherapy, and drugs.
today announced the initiation of a randomized clinical trial in Europe to assess the benefits of ablation using the Medtronic Arctic Front Advance(TM) cryoballoon as a first-line treatment for atrial fibrillation (AF) patients.
It added that anti-depressants remain the first-line treatment for mild and moderate depression despite a substantial weight of evidence, and advice from the Chief Medical Officer, that exercise on prescription can be as effective.
Boehringer Ingelheim has initiated a Phase III clinical study of BIBW 2992 as a first-line treatment for NSCLC (non-small cell lung cancer) patients with EGFR (epidermal growth factor receptor) mutations.
GEMZAR is indicated in combination with cisplatin (another type of chemotherapy) for the first-line treatment of patients with locally advanced (Stage IIIA or Stage IIIB) or metastatic (Stage IV or cancer that has spread) non-small cell lung cancer for whom surgery is not possible.
This is exactly what has happened recently, when evidence became available about its use as a first-line treatment.
For example, acyclovir is not AZT, and AZT was not available for first-line treatment of AIDS in the early 1980s; cholera is not slowly creeping into the Western Hemisphere, but it produced large epidemics in Central and South America in the 1990s; Figure 9.
There isn't enough evidence of safety and efficacy in many laboratories to label ablation as first-line treatment, he added.
In the survey, psychiatrists were asked to rate the appropriateness of treatments, with 9 being the treatment of choice, 7-8 being a first-line treatment, 4-6 a second-line treatment, 2-3 being a treatment rarely used, and 1 being a treatment that is never used.
Without the activism noted below, the price could have been more than twice as high--preventing the drug from ever being widely used for first-line treatment, where the need is not immediate and desperate, since other good treatments are available for these patients.
A rapidly increasing proportion of gonorrhea cases among men who have sex with men are resistant to a class of antibiotics commonly used to treat gonococcal infection, prompting the Centers for Disease Control and Prevention (CDC) to recommend that these drugs, fluoroquinolones, no longer be given as first-line treatment for this population.
First-line treatment of major depression with antidepressant medications in combination with nonpharmacologic interventions