Figure: US psoriasis patients progressing to drug therapy at second line and beyond following first-line therapy
failure (%, n), 2011
While many suggest that BTX A should be reserved for patients who have failed first-line therapy
, I would suggest that failing anticholinergic medication is likely a foregone conclusion.
The FDA's Psychopharmacologic Drugs Advisory Committee voted that quetiapine fumarate (Seroquel XR) is safe as an adjunctive therapy for major depressive disorder and generalized anxiety disorder, but only in certain instances as a first-line therapy
for MDD and not as a standalone treatment for GAD.
The approval of this trial represents an important step forward for Oncolytics, allowing us to move quickly into a treatment combination that could result in a first-line therapy
indication for REOLYSIN(R)," said Dr.
Even though other studies showed that elevations in triglyceride and cholesterol and body shape changes were also seen with the other classes of drugs and not just the protease inhibitors, the field had moved to using a non-nucleoside reverse transcriptase inhibitor (NNRTI)-based regimen as part of first-line therapy
Roland: A report will be published soon--probably in the January issue of Otolaryngology-Head and Neck Surgery--in which a consensus panel will recommend that ototoxic drops be avoided as first-line therapy
and be used only if there is a good reason to use something other than a drop that is not ototoxic.
Therefore, treatment strategies may be designed to operate at one or more of these pathways, with the least invasive methods being preferable as first-line therapy
Methyldopa is an old and frequently overlooked agent that, in the setting of hypertension in pregnancy, is suddenly transformed into first-line therapy
Although the results of the study were not as promising as other reports, Stika said she would still recommend methotrexate as a first-line therapy
for many women.
Following first-line therapy
, combination therapies become the mainstay of treatment regimens for the management of PHN, as physicians attempt to optimize therapeutic outcomes.
According to the new report entitled Treatment Algorithms in Major Depression, selective serotonin reuptake inhibitors (SSRIs), which include Lexapro, serve 61 percent of patients on first-line therapy
While doctors most likely consider tamoxifen a first-line therapy
for elderly women with advanced breast cancer, there has been little research showing that the treatment benefits these women, said Dr.