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first filial generation

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson 0.06 sec.
generation /gen·er·a·tion/ (jen″ĕ-ra´shun)
1. reproduction (1).
2. a class composed of all individuals removed by the same number of successive ancestors from a common predecessor, or occupying positions on the same level in a genealogical (pedigree) chart.

alternate generation  reproduction by alternate asexual and sexual means in an animal or plant species.
asexual generation  production of a new organism not originating from union of gametes.
first filial generation  the first-generation offspring of two parents; symbol F1.
parental generation  the generation with which a particular genetic study is begun; symbol P1.
second filial generation  all of the offspring produced by two individuals of the first filial generation; symbol F2.
sexual generation  production of a new organism from the zygote formed by the union of gametes.
spontaneous generation  the discredited concept of continuous generation of living organisms from nonliving matter.

first filial generation (F1),
the heterozygous offspring produced by the crossing of a homozygous dominant strain with a homozygous recessive strain.


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No developmental abnormalities have been observed in first filial generation (F1) male or female offspring resulting from mating finasteride-treated male rats (80 mg/kg/day; 61 times the human exposure) with untreated females.
 
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