ES of nerve terminals has been shown to induce rapid filopodial
sprouting in primary neuron cell cultures in the presence of extracellular [Ca.
1994) via prevention of filopodial
extensions from the endothelial tip cell in immature embryonic blood vessels (Theraponcos et al.
Formins are large multi-domain proteins required for the assembly of straight actin filaments found in the cytokinetic contractile ring, yeast actin cables, adherens junctions between epithelial cells and filopodial
protrusions (Chang et al.
From the tip of the neurite develops the growth cone, a filopodial structure.
As the growth cone moves through the environment, receptors on its filopodial structure allow maximum contact with the specific guidance signals, located within the extracellular matrix or the surface of nearby axons (Goldberg & Burmeister, 1989).
They suggested that it was the deposit of filopodial or lamellar protrusions that left cues, which later prompted the axon to branch from these new active sites.
In particular, rough endoplasmic reticulum and small primary lysosomes were predominant (Figure 5); the cell borders showed long filopodial expansions with a "hairy" appearance.
Under scanning electron microscopy, the alveolar macrophages were significantly altered, both in terms of size and of the characteristics of the cytoplasmatic surface, displaying two cell types: macrophages of medium size with narrow filopodial expansions and very large macrophages with short and wide expansions on the cellular surface.