However, our identification of this filarid
should help clarify the zoonotic role of filarioid infections in humans in tropical regions and increase awareness of physicians and ophthalmologists of the variety of nematodes that may be found in the human eye.
immitis venom allergen antigen 5-like (VA5) proteins as well as nucleic acid molecules that encode other structurally similar filarid
VA5 proteins, including those that encode O.
While the primary focus is development of a macrofilaricidal drug candidate for the treatment of onchocerciasis, it is expected that parallel screening of the closely related filarid
, Brugia malayi will also yield drug candidates for the treatment of lymphatic filariasis, a disfiguring and disabling neglected parasitic disease.