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field cancerization |
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field cancerization
Field carcinogenesis Molecular oncology The constellation of locoregional changes triggered by long-term exposure of a field of tissue to a carcinogen; FC may induce CA, CIS or dysplasia, which can be recognized
histologically; the remaining 'field,' despite adequate resection, is grossly normal but more susceptible to future CA; FC occurs in any embryologic tissue–eg, colorectal, breast ducts, bladder, bronchial, laryngeal epithelia, and
aerodigestive tract in tobacco exposure. See 'Cancerization.'. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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