fibrosis of the lungs

fibrosis of the lungs

Etymology: L, fibra + Gk, osis, condition; AS, lungen
the formation of scar tissue in the connective tissue of the lungs as a sequel to any inflammation or irritation caused by tuberculosis, bronchopneumonia, or a pneumoconiosis. Localized fibrosis may be complicated by infarction, abscess, or bronchiectasis. Also called pulmonary fibrosis.

Patient discussion about fibrosis of the lungs

Q. my uncle was diagnosed with pulmonary fibrosis. can anyone help?

A. Pulmonary Fibrosis involves scarring of the lung. Gradually, the air sacs of the lungs become replaced by fibrotic tissue. When the scar forms, the tissue becomes thicker causing an irreversible loss of the tissue’s ability to transfer oxygen into the bloodstream. Traditional theories have postulated that it might be an autoimmune disorder, or the after effects of an infection, viral in nature. There is a growing body of evidence which points to a genetic predisposition. A mutation in the SP-C protein has been found to exist in families with a history of Pulmonary Fibrosis. The most current thinking is that the fibrotic process is a reaction to microscopic injury to the lung. While the exact cause remains unknown, associations have been made with the following:*Inhaled environmental and occupational pollutants, *Cigarette smoking, *Diseases such as Scleroderma, Rheumatoid Arthritis, Lupus,*Therapeutic radiation. For full: http://www.pulmonaryfibrosis.org/ipf.htm Hope this helps.

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References in periodicals archive ?
QI WAS recently diagnosed with fibrosis of the lungs.
IPF is a life-threatening disease characterized by progressive scarring, or fibrosis of the lungs, which ultimately leads to respiratory failure.
A post mortem examination conducted by Dr Campbell Ritchie found that Mr Wallace had inhaled carbon particles from the steel which had caused fibrosis of the lungs, the inquest heard.
Cooke reported on fibrosis of the lungs caused by asbestos inhalation in 1924, but the term "asbestosis" was first used to describe it in 1927 (Cooke 1924, 1927).
An important indirect effect of interstitial lung disease, a broad category of lung diseases that includes some 150 disorders characterized by scarring or fibrosis of the lungs, is on the pulmonary vasculature with resulting pulmonary hypertension.
The disease results in scarring or fibrosis of the lungs and an irreversible loss of the lung tissues' ability to transport oxygen.
Food and Drug Administration (FDA) for the treatment of idiopathic pulmonary fibrosis (IPF), a disease characterized by progressive scarring or fibrosis of the lungs, which ultimately results in death.
The disease is characterized by progressive scarring, or fibrosis of the lungs, which ultimately leads to respiratory failure.
Data presented by our researchers at CHEST provide important insight to the potential anti-fibrotic and anti-inflammatory activity of our two Phase III compounds for IPF, which is characterized by inflammation and fibrosis of the lungs," stated Lawrence M.
today announced the publication of results from an exploratory Phase II clinical trial investigating the effects of Actimmune(R) (interferon gamma-1b) on the expression of biological markers associated with idiopathic pulmonary fibrosis (IPF), a disease characterized by progressive scarring or fibrosis of the lungs, which ultimately results in death.