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fibrosarcoma

   Also found in: Wikipedia 0.03 sec.
fibrosarcoma /fi·bro·sar·co·ma/ (-sahr-ko´mah) a malignant, locally invasive, hematogenously spreading tumor derived from collagen-producing fibroblasts that are otherwise undifferentiated.
ameloblastic fibrosarcoma  an odontogenic tumor that is the malignant counterpart to an ameloblastic fibroma, within which it usually arises.
odontogenic fibrosarcoma  a malignant tumor of the jaws, originating from one of the mesenchymal components of the tooth or tooth germ.

fi·bro·sar·co·ma (fbr-sär-km)
n.
A malignant tumor derived from fibrous connective tissue and characterized by immature proliferating fibroblasts or undifferentiated anaplastic spindle cells.

fibrosarcoma (fī´brōsärkō´m),
n a malignant mesenchymal tumor, the basic cell type being a fibroblast. Most fibrosarcomas are locally infiltrative and persistent but do not metastasize.
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Fibrosarcoma.
fibrosarcoma, odontogenic,
n an extremely rare malignant form of odontogenic fibroma.

fibrosarcoma
a sarcoma arising from collagen-producing fibroblasts. They occur in many organs and cause well-identified syndromes, e.g. oral, nasal, gastric.

odontogenic fibrosarcoma
a malignant tumor of the jaws, originating from one of the mesenchymal components of the tooth or tooth germ.

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The histologic differential diagnosis is predicated on whether the tumor is biphasic or monophasic; it includes adenocarcinoma, spindle cell carcinoma, fibrosarcoma, malignant peripheral nerve sheath tumor, glomangiopericytoma (hemangiopericytoma), leiomyosarcoma, malignant melanoma, epithelioid sarcoma, and angiosarcoma.
Seeking an explanation, Jian-Wei Gu and his colleagues at the University of Mississippi Medical Center in Jackson inoculated chick embryos with human fibrosarcoma cells, derived from a type of bone cancer.
In this new study titled Prevention of inflammation-mediated acquisition of metastatic properties of benign mouse fibrosarcoma cells by administration of an orally available superoxide dismutase, published in the British Journal of Cancer (2006), SOD/gliadin was shown to prevent the progression of tumors that are influenced by oxidative stress and inflammation in mice.
 
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