fibronectin


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fibronectin

 [fi″bro-nek´tin]
an adhesive glycoprotein: one form circulates in plasma and acts as an opsonin, and another is a cell-surface protein that mediates cellular adhesive interactions.

fibronectin

/fi·bro·nec·tin/ (-nek´tin) an adhesive glycoprotein: one form circulates in plasma and acts as an opsonin; another is a cell-surface protein that mediates cellular adhesive interactions.

fibronectin

(fī′brə-nĕk′tn)
n.
Any of a group of glycoproteins that are found especially in blood plasma and in the extracellular matrix of connective tissue and that play a role in cellular adhesion, embryonic differentiation, phagocytosis, and blood clotting.

FN1

A gene on chromosome 2q34 that encodes fibronectin, a glycoprotein present as a soluble dimer in plasma, and as a dimer or multimer on cell surfaces and in extracellular matrices. It plays central roles in cell adhesion and motility as required in embryogenesis, wound healing, blood coagulation, opsonisation, host defence, maintenance of cell shape and metastasis. It binds to collagen, fibrin, heparin, DNA and actin.

fi·bro·nec·tin

(fī'brō-nek'tin)
Any of various glycoproteins found on cell membranes and in blood and other body fluids; thought to function as adhesive ligandlike molecules. Possible roles in other processes include transformation to malignancy. Deficiency of fibronectin is associated with Ehlers-Danlos syndrome.
[L. fibra, fiber, + nexus, interconnection]

fibronectin

an adhesive glycoprotein; one form circulates in plasma, acting as an opsonin, another is a cell-surface protein which mediates cellular adhesive interactions.

Patient discussion about fibronectin

Q. Anyone can…..let me know…. I know that vomiting and nausea is sure for pregnancy and eager to know how early it can come? Anyone can…..let me know….

A. With both my preg. I started having terrible morning sickness right away, and my pregnancy's were 15 years apart! A Chiropractor suggested liquid Folic Acid and it turned out to be a real life saver for me! I couldn't have worked without it! I used it through both pregnancy's since my OBG's said it was perfectly safe to take.

Q. Could anyone let me know what causes depression? My friend is in a very depressed state, feels sad; a kind of hopelessness and ultimately lost interest in his favorite hobbies too. He doesn’t get required sleep and lacks energy…….he is taking antidepressants …..I am worried to a great extent as I am his very close friend. Could anyone let me know what causes depression?

A. No specific cause is linked to depression. Many factors are involved like genetic, biochemical, environmental & psychological as well. Genetic research has found that the multiple genes act together with other factor to cause it. Generally it’s triggered with some trauma leading to depression, which will be like losing someone close or a difficult relationship.

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A. Have you ever played basketball or just shot baskets?

More discussions about fibronectin
References in periodicals archive ?
Fibronectin regulated the DNA synthesis of fibroblasts.
Most researchers believe that fibronectin glomerulopathy is not an immune disease; thus, treatment with hormone and immunosuppressive therapies is inappropriate.
2006) Possible involvement of increase in spinal fibronectin following peripheral nerve injury in upregulation of microglial P2X(4), a key molecule for mechanical allodynia.
Taken together, the results show that aged muscle stem cells with compromised b1-integrin activity and aged muscles with insufficient amount of fibronectin both root causes of muscle aging.
Brecher, "Effect of hypertension on fibronectin expression in the rat aorta," Journal of Biological Chemistry, vol.
Accuracy of cervicovaginal fetal fibronectin test in predicting risk of spontaneous preterm birth: systematic review.
W]: 80 kD) and human plasma fibronectin were obtained from Sigma Aldrich (Saint Louis, MO) as well as all reagents used in functionalization.
Matrix metalloproteinases (MMPs) are a family of zinc enzymes responsible for the degradation of extracellular matrix components such as elastin, collagen, proteoglycans, laminin and fibronectin during tissue remodeling processes [45].
To analyze the potential for this protein in a mammalian infection, we created recombinant BB0347 and analyzed its binding to fibronectin in vitro.
Exposed bacteria also showed increased binding to human fibronectin and lung epithelial cells, compared with controls.
Coating of dishes or tissue culture flasks with extra cellular matrix proteins like collagen or fibronectin is a common procedure in laboratories involved in cell culture.
The swab test, which can be carried out from 22 weeks, looks for the presence of a protein called foetal fibronectin - a "glue-like" substance that bonds the developing baby to the uterus.