fibrogenic

fibrogenic

adjective Referring to or causing the formation of fibrous tissue; fibroplastic.
References in periodicals archive ?
The injury process in ARDS involves a complex interaction of numerous factors, including the release of proinflammatory cytokines, epithelial and endothelial cell damage, fibrogenic mediators, and abnormal lung mechanics.
Also, in patients with chronic hepatitis C infection, losartan decreased fibrosis progression and expression of fibrogenic genes (8).
In addition, they produce increased amounts of MMP-2 and its inhibiter, tissue inhibiter of metalloproteinase-2 (TIMP2), causing the fibrogenic response to proliferate due to destruction of the collagen in the basal membrane (collagen IV) and deposition of fibrillar collagen (collagen I) (Phillips et al.
Perhaps the most important finding here was the fact that neutralization of IL-33 signaling by blockade of the IL-33 receptor with anti-ST2 Ab inhibited both inflammatory and fibrogenic responses due to accompanying reduction in the IL33-induced expression of TNF-[alpha], CCL2, IL-13, and TGF-[beta]1.
CVC is a once-daily, oral, Phase III ready potent immunomodulator that blocks two chemokine receptors, CCR2 and CCR5, which are involved in inflammatory and fibrogenic pathways.
Bioactivity and stability of endogenous fibrogenic factors in platelet-rich fibrin.
Egr3 is implicated in neurodevelopment, learning and memory, immune response, and fibrogenic response [5-8], and this list shows functional diversity of this factor.
The leukocytes, in turn, not only attack and destroy hepatocytes, but also activate quiescent and activated HSCs, thereby exacerbating the fibrogenic response (Friedman 2008).
Expert consensus on an in vitro approach to assess pulmonary fibrogenic potential of aerosolized nanomaterials.
Resveratrol inhibits paraquat- induced oxidative stress and fibrogenic response by activating the nuclear factor erythroid 2-related factor 2 pathway.
Beyond the multiple cell types (inflammatory cells, epithelial cells, fibrogenic effector cells, endothelial cells, and others) involved in the fibrogenic response, three cellular signal transduction pathways play leading roles in the process of fibrosis: transforming growth factor-beta (TGF-[sz]), mitogen-activated protein kinases (MAPKs) and integrins.
Talc has been shown to be fibrogenic due to an immunological response [1].