10) MRI, owing to its inherently excellent soft-tissue contrast, is of great value in demonstrating excess fibrofatty
tissue, which has signal characteristics similar to subcutaneous fat, showing high signal intensity on T1-weighted, intermediate signal on T2-weighted, and low signal on fat-suppressed.
ARVD/C is an inherited cardiomyopathy with right ventricular dysfunction due to fibrofatty
replacement of myocardium, predisposing to ventricular tachycardia and death.
Smad expression in human atherosclerotic lesions: evidence for impaired TGF-beta/Smad signaling in smooth muscle cells of fibrofatty
MRI criteria for CD include involvement of the terminal ileum, enhancement of the entire bowel wall (full thickness and transmural enhancement), relative sparing of the rectum, wall thickening, increased SI of bowel wall and surrounding fat, asymmetry, skip lesions, fistulae, infiltration of fat around inflamed bowel wall, abscesses, lymphadenopathy, and fibrofatty
2) There may be fibrofatty
thickening of the mesentery with inflammatory changes ranging from fatty necrosis to mesenteric fibrosis, retraction and calcification.
tissue replaces renal parenchyma that has atrophied because of chronic inflammation.
Grossly, the parotid gland was made up of yellow-tan fibrofatty
tissue with no identifiable lesions or nodules.
The yellow-red and pink, fibrofatty
tumor measured 6.
Surgical exploration revealed that an encapsulated, fibrofatty
nodular mass extended from the hyoid bone down to the supraclavicular fossa.
replacement presents with diffuse or segmental replacement of RV myocardium with scar in the DE-MRI images (Figure 17).
Microscopically, the specimen showed fibrofatty
tissue with chronic inflammation and focal hemosiderin deposits.
5) Two pathologic types of ARVC have been proposed: a variant of ARVC characterized exclusively by fat replacement and a variant with fibrofatty
replacement of myocytes.