FGF12

(redirected from fibroblast growth factor 12)

FGF12

A gene on chromosome 3q28 that encodes fibroblast growth factor 12 of the FGF family, which bind heparin and have a broad range of cellular activities, including cell survival, division, differentiation and migration, embryonic development, morphogenesis, tissue repair, tumour growth and invasion. FGF12’s function is unknown; it lacks the N-terminal signal sequence found in most other FGF family members, but has clusters of basic residues which act as a nuclear localisation signal. It is highly expressed in embryonic retina, olfactory epithelium, olfactory bulb, and segmentally in the body wall. It is thought to play a role in nervous system development and function.
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Fibroblast growth factor 1 fgf1 NM_012846 Fibroblast growth factor 2 fgf2 NM_019305 Fibroblast growth factor 3 fgf3 NM_130817 Fibroblast growth factor 9 fgf9 NM_012952 Fibroblast growth factor 11 fgf11 NM_130816 Fibroblast growth factor 12 fgf12 NM_130814 Fibroblast growth factor 13 fgf13 NM_053428 Fibroblast growth factor 14 fgf14 NM_022223 Fibroblast growth factor 15 fgf15 NM_130753 Fibroblast growth factor 17 fgf17 NM_019198 Fibroblast growth factor 18 fgf18 NM_019199 Fibroblast growth factor 20 fgf20 NM_023961 Fibroblast growth factor 21 fgf21 NM_130752 Fibroblast growth factor 22 fgf22 NM_130751 Fibroblast growth factor 23 fgf23 NM_130754 Fibroblast growth factor fgfr1 NM_024146 receptor 1 Fibroblast growth factor fgfr2 BF 557.
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