fibrinopeptide


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fibrinopeptide

 [fi″brĭ-no-pep´tīd]
either of two peptides (A and B) split off from fibrinogen during blood clotting by the action of thrombin.

fi·brin·o·pep·tide

(fī'brin-ō-pep'tīd),
One of two pairs of peptides (A and B) released from the amino-terminal ends of 2α- (or Aα-) and 2β- (or Bβ-)chains of fibrinogen by the action of thrombin to form fibrin; they have a vasoconstrictive effect.

fibrinopeptide

/fi·bri·no·pep·tide/ (fi-brin″o-pep´tīd) either of two peptides (A and B) split off from fibrinogen during coagulation by the action of thrombin.

fibrinopeptide

[fī′brinōpep′tīd]
Etymology: L, fibra + Gk, peptein, to digest
either of two peptides (A and B) split off from fibrinogen by the action of thrombin. See also fibrinogen, thrombin.

fi·brin·o·pep·tide

(fī'brin-ō-pep'tīd)
One of two pairs of peptides (A and B) released from the amino-terminal ends of 2α- and 2β-chains of fibrinogen by the action of thrombin to form fibrin; has a vasoconstrictive effect.

fibrinopeptide

either of two peptides (A and B) split off from fibrinogen during blood clotting by the action of thrombin.
References in periodicals archive ?
Fibrinopeptide A level and left ventricular ejection fraction were the only independent predictors of cardiac death (J.
Congenital dysfibrinogenemia characterized by defective release of fibrinopeptide A and fibrinogen degradation products.
26) Thrombin mediates fibrin clot formation by cleaving 2 molecules each of fibrinopeptide A and fibrinopeptide B from fibrinogen, producing fibrin monomer.
After 25 min, the resulting clot was recovered by winding around a glass rod; the supernatant was retained for fibrinopeptide isolation.
D-dieter appears to be more sensitive than other hemostatic markers, such as fibrinopeptide A and B-thromboglobulin, particularly for cardioembotic stroke (16, 17).
Each fibrinogen molecule releases up to 2 fibrinopeptide A and B molecules (38, 39), giving molar concentrations of fibrinopeptides among the most abundant serum components.
Through the course of thrombin activation, fibrinogen has been shown to release 3 major forms of fibrinopeptide A (FPA) (13): the unmodified form ADSGEGDFLAEGGGVR (FPA), which constitutes ~70%, an NH2-terminal truncated FPA (des-Ala FPA; ~10%), and a product in which Ser-3 is phosphorylated (P-FPA; ~20%).
Urine and plasma levels of fibrinopeptide B in patients with deep vein thrombosis and pulmonary embolism.
The use of fibrinopeptide A as a marker of fibrin formation is limited because of preanalytical and technical difficulties (10).
Epidemiological and genetic associations of activated factor XII concentration with factor VII activity, fibrinopeptide A concentration, and risk of coronary heart disease in men.
The formed thrombin cleaves fibrinopeptide A (FPA) from fibrinogen, producing fibrin.