fibrinolytic agents


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fibrinolytic agents,

n.pl agents that decrease the breakdown of fibrin.
References in periodicals archive ?
Only 58% of eligible patients received fibrinolytic agents within 12 hours.
Interhospital transfer delays, while clearly problematic, could be mitigated if fibrinolytic agents were rapidly administered at the receiving hospital.
The latter findings in our study also call for immediate attention and should serve to encourage the development of written protocols at referring institutions to assure a most expedite clinical assessment of patients, the enhancement of those institutions for utilizing fibrinolytic agents in suitable candidates and the timely referral to PCI-capable facilities of those patients that are still within the time frame for beneficial results from catheter-based reperfusion.
Patient demographic and clinical characteristics included sociodemographic variables (gender, age); medical history (hypertension, diabetes, dyslipidemia); the admission time of day (day, evening, or night); and admission day of week (weekday or weekend), the presence of chest pain, the location of myocardial infarction, the fibrinolytic agent used, the percentages of post-fibrinolytic TIMI-3 flow, and post-fibrinolytic CABG.
Both groups had similar ages and similar percentages of men, hypertension, diabetes, dyslipidemia, chest pain, and anterior wall infarctions on presentation, the use of streptokinase as the fibrinolytic agent, and similar percentages of TIMI-3 flow restoration, and the need for coronary artery bypass grafting.
The use of various fibrinolytic agents (streptokinase, urokinase, and recombinant tissue-type plasminogen activator [rt-PA]) has been reported in a small number of clinical series with a very limited number of participants, yielding significant variability regarding inclusion criteria, treatment protocol, and outcome analysis.
Therefore, genotyping of this polymorphism may become relevant to risk assessment and to the selection and dosing of patients being treated with anticoagulant and fibrinolytic agents, in particular with tissue plasminogen activator.
Thrombolysis with various fibrinolytic agents has been described in cases with occluded shunts, as an alternative or adjuvant therapy to balloon angioplasty.
When compared with older fibrinolytic agents, RETAVASE distinguishes itself by its ease of administration - a simple two-bolus injection given 30 minutes apart.
Previous studies of full-dose fibrinolytic agents, commonly referred to as clot busters, have reported that less than 50 percent of heart attack patients achieved normal restoration of blood flow within 60 minutes.
Fibrinolytic agents are used to treat patients who suffer from heart attacks.