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fibrinoid necrosis

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fibrinoid necrosis
'Smudgy' eosinophilic fibrin-like deposits, of degenerated collagen or ground substance, in arterial walls of Pts with malignant HTN and periarteritis nodosa; FN may also occur in the Arthus reaction, acute rheumatic fever, SBE, near peptic ulcers, rheumatoid arthritis, immune complex disease, HBV, malignancy, complement C2 deficiency, Henoch-Schönlein purpura, SLE and other collagen vascular diseases. See Fibrosis, Necrosis.


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plexiform lesions or fibrinoid necrosis of vessels were not observed in the obese or morbidly obese subjects (from Pulmonary and Cardiovascular Complications of Obesity-Haque et al) 4.
Microscopically, most of the hemorrhagic foci in the brain consisted of fibrinoid necrosis of the wall of small veins, surrounded by hemorrhagic parenchymal necrosis and a dense annular infiltrate of neutrophils and macrophages (Figure).
 
 
 
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