fibrinogen (redirected from fibrinogen deficiency)

fibrinogen /fi·brin·o·gen/ (fi-brin´o-jen) coagulation factor I.

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fi·brin·o·gen (f-brn-jn)

n.

A protein in the blood plasma that is essential for the coagulation of blood and is converted to fibrin by thrombin and ionized calcium. Also called factor I.

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Fibrinogen

A type of blood protein called a globulin that interacts with thrombin to form fibrin.

Mentioned in: Prothrombin Time

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fibrinogen

[fībrin′əjən]

Etymology: L, fibra, fiber; Gk, genein, to produce

a plasma protein that is converted into fibrin by thrombin in the presence of calcium ions. Also called factor I. Compare fibrin. See also afibrinogenemia, blood clotting, fibrinolysis, thrombin.

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fibrinogen [fi-brin´o-jen]

a high-molecular-weight protein in the blood plasma that by the action of thrombin is converted into fibrin; called also factor i. In the clotting mechanism, fibrin threads form a meshwork for the basis of a blood clot. Most of the fibrinogen in the circulating blood is formed in the liver. Normal quantities of fibrinogen in the plasma vary from 100 to 700 mg per 100 ml of plasma.

Commercial preparations of human fibrinogen are used to restore blood fibrinogen levels to normal after extensive surgery, or to treat diseases and hemorrhagic conditions that are complicated by afibrinogenemia.

fibrinogen degradation products fragments of fibrinogen or fibrin degraded by plasmin, which are found in the serum and urine of patients with disseminated intravascular coagulation (DIC) and in the urine of patients who have had renal transplants.

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fibrinogen

(fībrin´jn)
(factor I, profibrin),
n a soluble plasma protein (globulin) that is acted on by thrombin to form fibrin. The normal level is 200 to 400 mg/100 ml in plasma. Coagulation is impaired if the concentration is less than 100 mg/100 ml. Another form called
tissue fibrinogen, which has the power of clotting the blood without the presence of thrombin, occurs in body tissues.

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fibrinogen

a high-molecular-weight protein in the blood plasma that by the action of thrombin is converted into fibrin; called also clotting factor I. In the clotting mechanism, fibrin threads form a meshwork for the basis of a blood clot. Most of the fibrinogen in the circulating blood is formed in the liver. Elevations in the blood are nonspecific indicators of inflammatory disease.

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fibrinogen deficiency

may be due to afibrinogenemia, hypofibrinogenemia or dysfibrinogenemia.

fibrinogen degradation products (FDPs)

see fibrin-fibrinogen degradation products.

fibrinogen split products

see fibrin-fibrinogen degradation products.

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fibrinogen

Coagulation factor I, factor I Hematology A soluble 340 kD plasma glycoprotein required for normal platelet function and wound healing; it is converted into fibrin in the common pathway of coagulation, and provides physical scaffolding for permanent hemostatic plugs, which is orchestrated under thrombin's baton; fibrinogen is an 'acute phase reactant,' which may be markedly ↑ in various types of nonspecific stimuli–eg, inflammation, hemostatic stress, pregnancy, autoimmune diseases; it is ↑ in hyperfibrinogenemia; ↓ in afibrinogenemia

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Patient discussion about fibrinogen.

Q. What Are the Risk Factors for Developing Breast Cancer? I am 35 years old. My mother had breast cancer when she was 60 and my aunt had it when she was 52. Am I at increased risk for developing the disease? Are there other risk factors?

A. Here are some risk factors :
- Age. your chances of developing breast cancer increase with age
- Personal history of breast cancer. if you had cancer in one breast, you have increased risk in developing cancer in your other breast
- Family history. Yes, it is genetically related, so you're at risk..
- Radiation exposure
- Early onset of menstrual cycle
- Late menopause
- First pregnancy in older age
- Race
- Hormone therapy
- Some birth control pills
- Smoking and excessive consumption of alcohol

Q. What are the risk factors for breast cancer? What are the risk factors for breast cancer?

A. Here are some risk factors :
- Age. your chances of developing breast cancer increase with age
- Personal history of breast cancer. if you had cancer in one breast, you have increased risk in developing cancer in your other breast
- Family history. Yes, it is genetically related, so you're at risk..
- Radiation exposure
- Early onset of menstrual cycle
- Late menopause
- First pregnancy in older age
- Race
- Hormone therapy
- Some birth control pills
- Smoking and excessive consumption of alcohol

Q. What Are the Risk Factors for Ovarian Cancer? My neighbor has recently found out she has ovarian cancer. Are there any known risk factors for this disease?

A. Well I was diagnosed with ovarian cancer, at the age of 41, was on birth control pills, no family history of it ,was pregnant x2. I had no risk factors.