fibrin-fibrinogen degradation products


Also found in: Acronyms.

fibrin-fibrinogen degradation products

Fibrin 'splits' Hematology Polypeptide fragments of fibrin degradation, which are generated by unchecked 1º fibrinolysis. See Disseminated intravascular coagulation.
Fibrin degradation products
Intravascular lesions Associated with DIC, DVT, and PTE–ie, pathological fibrinolysis
Extravascular conditions eg, hematomas, neoplasia, sepsis, allograft rejection, glomerular disease, severe liver disease and obstetric complications, eg abruptio placentae, eclampsia, retained dead fetus

fibrin-fibrinogen degradation products

A group of soluble protein fragments produced by the proteolytic action of plasmin on fibrin or fibrinogen. These products impair the hemostatic process and are a major cause of hemorrhage in intravascular coagulation and fibrinogenolysis.