fibrin glue

fibrin

an insoluble protein that is essential to clotting of blood, formed from fibrinogen by action of thrombin.

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fibrin-fibrinogen degradation products (FDPs)

the breakdown products of fibrin and fibrinogen, resulting from activation of the fibrinolytic system, they inhibit fibrin formation and platelet adherence. Elevated levels are found in the blood and urine in association with disseminated intravascular coagulation and detection is a test for that condition.

fibrin-fibrinogen split products

see fibrin-fibrinogen degradation products (above).

fibrin foam

a clot promoting surgical material for application to oozing surfaces. Strips of fine white sponge to be soaked in thrombin solution before application.

fibrin glue

a mixture of bovine thrombin and concentrated fibrinogen. It may be used topically or by injection in management of hemostasis.

fibrin plate method

a method of measuring fibrinolytic activity by incubating a fibrin clot with test serum in a Petri dish.

soluble fibrin monomers

a stage in the clot formation process of producing insoluble fibrin monomers.

fibrin stabilizing factor

see fibrin stabilizing factor.

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fibrin glue

Fibrin sealant Surgery A liquid commercial product composed of purified fibrinogen and thrombin used to seal operative wounds, by partially re-enacting the final stage of the coagulation cascade, in which fibrinogen is converted to fibrin in the presence of thrombin, factor XIII, fibronectin and calcium ions; FS are mixed at the 'table,' and used to seal complex surgical wounds–eg, anorectal fistulas