Fibrin

fibrin /fi·brin/ (fi´brin) an insoluble protein that is essential to clotting of blood, formed from fibrinogen by action of thrombin.

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fi·brin (fbrn)

n.

An elastic, insoluble, whitish protein derived from fibrinogen by the action of thrombin and forming an interlacing fibrous network in the coagulation of blood.

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fibrin·ous adj.

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Fibrin

The last step in the coagulation process. Fibrin forms strands that add bulk to a forming blood clot to hold it in place and help "plug" an injured blood vessel wall.

Mentioned in: Antibiotic-Associated Colitis, Empyema, Fibrinogen Test, Hemophilia, Prothrombin Time

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fibrin (fīˑ·brin),

n white, insoluble protein that makes up a blood clot by forming a network in which red blood cells and platelets are trapped; formed by the action of thrombin on fibrinogen.

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fibrin

an insoluble protein that is essential to clotting of blood, formed from fibrinogen by action of thrombin.

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fibrin-fibrinogen degradation products (FDPs)

the breakdown products of fibrin and fibrinogen, resulting from activation of the fibrinolytic system, they inhibit fibrin formation and platelet adherence. Elevated levels are found in the blood and urine in association with disseminated intravascular coagulation and detection is a test for that condition.

fibrin-fibrinogen split products

see fibrin-fibrinogen degradation products (above).

fibrin foam

a clot promoting surgical material for application to oozing surfaces. Strips of fine white sponge to be soaked in thrombin solution before application.

fibrin glue

a mixture of bovine thrombin and concentrated fibrinogen. It may be used topically or by injection in management of hemostasis.

fibrin plate method

a method of measuring fibrinolytic activity by incubating a fibrin clot with test serum in a Petri dish.

soluble fibrin monomers

a stage in the clot formation process of producing insoluble fibrin monomers.

fibrin stabilizing factor

see fibrin stabilizing factor.