FBN2

(redirected from fibrillin 2)

FBN2

A gene on chromosome 5q23-q31 that encodes fibrillin 2, a member of the fibrillin family of glycoproteins, which is a component of connective tissue microfibrils and involved in elastic fibre assembly.

Molecular pathology
FBN2 mutations cause congenital contractural arachnodactyly.
References in periodicals archive ?
5,6] Molecular analysis of Marfan-like conditions has unveiled that patients with congenital contractural arachnodactyly (CCA or Beals syndrome) carry germline mutations of the fibrillin 2 (FBN2) gene on chromosome 5q23-q31.
3 2e-61 Sidekick 2 Hemicentin NM_031935 1e-99 Hemicentin 1 Matrilin 1 BC131710 2e-40 Matrilin 1 Matrilin 2 AB209735 3e-107 Fibrillin 2 Netrin 1 NM_004822 4e-160 Netrin 1 Netrin G1 BC113455 7e-119 Laminin, beta 1 Osteomodulin BC128989.