fetotoxicity

fetotoxicity

 [fe″to-tok-sis´ĭ-te]
toxic effects on a fetus of a substance that crosses the placental barrier; see also embryotoxicity. adj., adj fetotox´ic.

fetotoxicity

Toxicology Adverse fetal effects due to toxins entering the maternal circulation and crossing the placental barrier, which may compromise maternal health and appear as fetal malformations, altered growth and in utero death. Cf Embryotoxicity.
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References in periodicals archive ?
Embryotoxicity and fetotoxicity following intraperitoneal administrations of hexavalent chromium to pregnant rats.
For example, Attention Deficit and Hyperactivity Disorder (ADHD) is connected to cognitive impairment, behavioral problems, low birth weight and fetotoxicity.
Oshima-Franco, "Assessment of cytotoxicity, fetotoxicity, and teratogenicity of Plathymenia reticulata benth barks aqueous extract," BioMed Research International, vol.
Preliminary studies had shown that the positive control of 10 mg/kg CP was suitable for studying transplacental genotoxicity, as it shows a significant increase in MN frequency but not significant fetotoxicity.
In general, because of fetotoxicity of ACE inhibitors and angiotensin II receptor antagonist drugs, these agents should be avoided in pregnancy and lactation.
Therefore, the copaiba oil delivered in the vaginal cream, in the concentration employed, did not determine the appearance of fetotoxicity.
Fetotoxicity and death of offspring are reported in guinea pigs at doses of 4.
Animal investigations have confirmed the embryotoxicity and fetotoxicity of DMSA, and it has been suggested that this toxicity might be mediated through changes in copper and zinc metabolism (47-50).
Numerous studies have shown Se supplementation counteracts the negative impacts of exposure to Hg, particularly in regard to neurotoxicity, fetotoxicity, and developmental toxicity.
vascular lesions, chloracne, teratogenicity, fetotoxicity, impaired reproductive performance, endometriosis and delayed death.