11,71) Similar to other maternal infections (eg, TORCH agents) and fetotoxic
insults, exposure in the latter half of pregnancy, after cortical organization is largely completed, may result in less overt neurologic or other impairments that may be detected only later in life.
alata leaves at the oral doses of 250, 500 and 1000 mg/kg body weight on daily basis from days 10 until day 18 post-coitum exhibited several potential effects on the maternal and fetal outcomes of pregnant rats (anti-implantation, anti-gonadotropic, anti-progesteronic, selective estrogenic, embryonic resorption and fetotoxic
activities), but it could not induce abortion in the animals.
effects of nickel in drinking, water in mice.
It is reported that Aloe vera extracts are not fetotoxic
and have no abortus effect (Parry & Matambo, 1992).
These products can act as a potential source of fetotoxic
cytokines that can effect the onset of labor by signaling the body that it is time for delivery, irrespective of the age of the fetus.
Although oral and inhalation exposures did not have embryotoxic or fetotoxic
effects, high doses through both of these mediums reduced weight gain (Dorman et al.
Treatment with MAO-B inhibitors, which are embryotoxic and fetotoxic
at high doses in animals, should be avoided during pregnancy.
Ticlid is fetotoxic
in mice, rabbits, and rats, but is not teratogenic.
Even low-level CO exposures can have cardiovascular, neurobehavioral, and fetotoxic
Others are potentially carcinogenic, including cobalt and vanadium, and still more are fetotoxic
(harmful to fetuses), including aluminum, copper, barium, lead, and manganese.
7,11) Produced locally in the periodontal tissues, inflammatory mediators such as TNF-[alpha] and PGE2 can act as a potential systemic source of fetotoxic
cytokines due to the high vascularity of the periodontium.
They also had prenatal co-exposure to the fetotoxic
pesticide chlorpyrifos (Whyatt et al.