Nicotine through higher secretion of catecholamines increased lipolysis and levels of plasma-free fatty acids resulting in higher concentrations of oxidatively modified lipid products in mothers as well as fetoplacental units
Doppler velocimetry in 5 patients showed elevated S/D ratio in umbilical artery and normal S/D ratio in middle cerebral artery, suggesting increased resistance in fetoplacental unit
We evaluated the co-culture of H295R and BeWo cells as a model of steroidogenesis and, specifically, of estrogen production in the fetoplacental unit and its disruption by chemical exposures.
We have succeeded in developing a co-culture of H295R human adrenocortical carcinoma cells with characteristics of the fetal adrenal and BeWo human choriocarcinoma cells with characteristics of the villous trophoblast that exhibits the steroidogenic functionality of the human fetoplacental unit.
In prenatal screening, maternal serum concentrations of secretory products of the fetoplacental unit
in combination with maternal age are used to determine a woman's risk of having a fetus affected with Down syndrome.
He found an association between the vascular reduction of fetoplacental unit
and loss of functional placental tissue with the lesions like macroscopic and microscopic infarction, thickness of placental membranes, avascular villi and tissue ischemia which are significant.
7) However, it soon became evident that relatively low hCG levels and the lack of a normal fetoplacental unit
also result in reduced progesterone production by the corpus luteum.
Maternal physiologic changes in pregnancy occur as a result of hormonal alterations, mechanical effects of the gravid uterus, increased metabolic and oxygen requirements, metabolic demands of the fetoplacental unit
, and hemodynamic alterations associated with the placental circulation.
9) Partly attributable to an iron deficit during pregnancy caused by the increased iron demands of the fetoplacental unit
and an increased maternal red cell mass.
Most of these are due to de novo production of variety of protein and steroid hormones by fetoplacental unit
as well as by the increased activity of maternal pituitary, thyroid, adrenal glands (2).
Doppler is a rapid noninvasive test to know the hemodynamic condition of the fetoplacental unit
There is a shift in the amino acid transport capacity and metabolic pathways within the fetoplacental unit
and has disrupted insulin/IGF signalling in liver and muscle account leading to decreased fetal growth.