Of much concern is the increased risk of fetal overgrowth and long-term health consequences for children of obese mothers.
The research tells us that, while we may be able to reduce excessive gestational weight gain, it is unlikely that we will be successful in reducing fetal overgrowth, GDM, or preeclampsia in obese women.
However, they were taller than control and asymmetric LGA newborns, providing indirect evidence of a genetic cause in symmetric fetal overgrowth.
Maternal constraint refers to the limited capacity of the uterus to support fetal growth and is important to limit fetal overgrowth.
Loss of the imprinted Igf2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth
and perinatal lethality.
Jirtle's team is focusing on the finding's implications for cancer, but it might explain why people are less susceptible than some animals to fetal overgrowth
Human embryos appear relatively immune to such laboratory-induced alterations, as evidenced by the fact that fetal overgrowth
rarely occurs with vitro fertilization or other types of assisted reproduction.
Neonates of women who would be added to the diagnosis of gestational diabetes mellitus by criteria established by the International Association of the Diabetes and Pregnancy Study Groups had greater measures of fetal overgrowth
, compared with controls.
Many of us also have delivered babies with significant adiposity, sometimes perilously low blood glucose, shoulder dystocia, nerve injuries, and other complications that typically occur as a consequence of fetal overgrowth
The risk of cesarean delivery and associated morbidities increases as well, as does the risk of macrosomia and fetal overgrowth
(an increase in adipose tissue rather than lean body mass).
Treating mild gestational diabetes lowered the risks of fetal overgrowth
, shoulder dystocia, cesarean delivery, and gestational hypertension, as well as decreasing maternal weight gain, based on a study of almost 1,000 women.
Short term, there is an increased risk of adverse obstetric outcomes related to fetal overgrowth
and higher birth weight.