fetal lung maturity


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fetal lung maturity

Obstetrics A parameter that determines the likelihood a neonate will develop RDS; infants delivered at 40 ± 2 wks have 0% incidence of RDS; at 36 wks 0-2%, at 34 wks 8-34%–depending on birthweight

fetal lung maturity

The ability of the developing lung to oxygenate and ventilate effectively outside the womb. The lungs are the last fetal organ to mature. Surfactant, which allows the alveoli in the lungs to expand and not stick together, is secreted by the fetal lungs after 28 weeks. The readiness of the fetal lung can be assessed with several invasive, e.g., amniocentesis, and noninvasive, e.g., ultrasound, tests, all of which have some shortcomings. Some tests on amniotic fluid include: measurements of surfactant; phosphatidylglycerol; the lecithin/sphingomyelin ratio; and the number of lamellar bodies.

Patient care

Premature infants born with immature lungs have a high likelihood of developing infantile respiratory distress syndrome. Antenatal treatment with glucocorticoids improves most amniotic fluid indices of fetal lung maturity. Infants born with immature lungs are also often treated with continuous positive airway pressure, other forms of mechanical ventilation, and surfactant.

See also: maturity
References in periodicals archive ?
Neonatal outcomes after demonstrated fetal lung maturity before 39 weeks of gestation.
Multicenter evaluation of TDx test for assessing fetal lung maturity.
Refrigerated and frozen amniotic fluid for fetal lung maturity testing and lamellar body density counts.
Evaluation of lamellar body number density as the initial assessment in a fetal lung maturity test cascade.
Amniotic fluid lamellar body count: a rapid and reliable fetal lung maturity test.
Determination of fetal lung maturity by fluorescence polarization of amniotic fluid.
Is fluorescent polarization reliable and cost efficient in a fetal lung maturity cascade?
A comparison of the accuracy of the infrared spectroscopy and TDx-FLM assays in the estimation of fetal lung maturity.
Prospective clinical evaluation of an improved fluorescence polarization assay for predicting fetal lung maturity.
Clinical evaluation of the NBD-PC fluorescence polarization assay for prediction fetal lung maturity.
However, it's not until 39 weeks that you can be assured of fetal lung maturity," commented Dr.
Among 37 patients who underwent amniocentesis for genetic screening and 10 who had the test at term to determine fetal lung maturity, none had hepatitis B DNA when measured by dot-blot hybridization or polymerase chain reaction (PCR) testing.