ferritin


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ferritin

 [fer´ĭ-tin]
the complex of iron and apoferritin, a major form in which iron is stored in the body.

fer·ri·tin

(fer'i-tin),
An iron-protein complex, containing up to 23% iron, formed by the union of ferric ions with apoferritin; it is found in the intestinal mucosa, spleen, bone marrow, reticulocytes, and liver, and regulates iron storage and transport from the intestinal lumen to plasma.
See also: apoferritin.

ferritin

/fer·ri·tin/ (-ĭ-tin) the iron-apoferritin complex, one of the chief forms in which iron is stored in the body.

ferritin

(fĕr′ĭ-tĭn)
n.
An iron-containing protein complex, found principally in the intestinal mucosa, spleen, and liver, that functions as the primary form of iron storage in the body.

ferritin

[fer′itin]
Etymology: L, ferrum, iron
an iron compound formed in the intestine and stored in the liver, spleen, and bone marrow for eventual incorporation into hemoglobin. Serum ferritin levels are used as an indicator of the body's iron stores. Normal adult blood levels are 12 to 300 ng/mL for males and 10 to 150 ng/mL for females.

ferritin

Hematology A major iron storage protein present in small amounts in serum; in healthy adults, serum ferritin reflects the body's iron store, and can be used to detect iron deficiency Ref range ♂ 33-236 ng/mL; ♀, < 40 yrs 12-263 ng/mL; > 40 yrs 11-122 ng/mL; ↓ Ferritin Hypochromic anemia, microcytic anemia. iron deficiency anemia↑ Ferritin Iron overload, hemochromatosis, inflammation, malignancy

fer·ri·tin

(fer'i-tin)
An iron protein complex, containing up to 23% iron, formed by the union of ferric iron with apoferritin; it is found in the intestinal mucosa, spleen, bone marrow, reticulocytes, and liver, and regulates iron storage and transport from the intestinal lumen to plasma.

ferritin

The principal IRON-binding protein of the body. Ferritin acts as an iron store in the liver and other tissues. Each ferritin molecule can hold up to 4500 iron atoms and the amount of iron in ferritin molecules accurately reflects the total iron stores of the body. Ferritin also protects against the toxic effects of excess iron.

ferritin

a conjugated, electron-dense protein concerned in the absorption of iron through the intestinal mucosa. It serves as a storage protein for iron in the liver and spleen.

Ferritin

A protein found in the liver, spleen, and bone marrow that stores iron.
Mentioned in: Iron Tests

ferritin

an iron-protein complex, which acts as a store for iron. Found mainly in the liver but also in the spleen and bone marrow. Serum ferritin measurement is used as a marker of total body iron. See also anaemia.

ferritin

water-soluble iron-protein complex, used in haemoglobin formation

fer·ri·tin

(fer'i-tin)
An iron protein complex, containing up to 23% iron, formed by the union of ferric iron with apoferritin; it is found in the intestinal mucosa, spleen, bone marrow, reticulocytes, and liver.

ferritin (fer´itin),

n the compound iron-appoferritin, which is produced in the intestine and stored primarily in the liver, spleen, and bone marrow. It eventually becomes a component of hemoglobin and can be measured to estimate the body's iron levels.

ferritin

the iron-apoferritin complex, one of the forms in which iron is stored in the body.

Patient discussion about ferritin

Q. My Iron/TIBC tests normal, Ferritin,Serum = 22. Range 22-322. What is the problem? Iron Bind. Cap. ug/dL 324 range 250 - 450 UIBC ug/dL 206 range 150 - 375 Iron, Serum ug/dL 118 range 40 - 155 Iron Saturation % 36 range 15 - 55 Biopsy = Prostate Cancer....PCA high = 10.2 PSA now 8.3 PSA Ultra W/Serial Monitor ...Ultrasenitive = 8.26

A. What makes you think something is not normal? Ferritin values may be low in some people, and iron deficiency is usually defined as ferritin 15. Do you have anemia? Currently, it doesn't seem you have any problem with the iron levels.

Take care,

More discussions about ferritin
References in periodicals archive ?
Although adequate evidence shows that [iron] supplementation increases hemoglobin and ferritin levels, the evidence is unclear on whether this increase leads to an improvement in maternal and fetal outcomes.
Comparison of the efficacies of oral iron and pramipexole for the treatment of restless legs syndrome patients with low serum ferritin.
Ferritin can be produced in apparently unlimited amounts by virtually all cells in response to excess intracellular iron (2) and augmented by inflammatory cytokines primed in a positive feedback manner by iron excess (3).
Furthermore, the serum ferritin concentration was significantly increased and the serum transferrin level was significantly decreased in the IDA (10.
A review of charts of pediatric patients with elevated ferritin level at a large pediatric hospital in 2007 revealed that a ferritin level of more than 10,000 ng/mL was 90% sensitive and 96% specific for HLH.
If the test reveals your blood ferritin levels are lower than normal, it indicates your body's iron stores are low and you have iron deficiency.
Baslangic ortalama ferritin ve cinko degerleri gruplar arasinda istatistiksel olarak farkli degildi (ortalama ferritin: 4.
Most stored iron is located in ferritin, yet ferritin iron does not stimulate ROS formation.
Ferritin was fused genetically with hemagglutinin (HA), the protein found on the surface of the influenza virus, resulting in a nanoparticle with eight protruding viral spikes.
Search terms included hemochromatosis, haemochromatosis, hereditary hemochromatosis, diet, iron, absorption, ironoverload, tea, polyphenol, tannin, gallic acid, gallate, ferritin, wine and coffee in various combinations.