fenfluramine /fen·flur·amine/ (fen-flldbomacr´ah-mēn) an amphetamine derivative, formerly used as an anorectic in the form of the hydrochloride salt.
fenfluramine
fen·flu·ra·mine (f n-fl r  -m n )n. A fluorinated compound that is used in the treatment of refractory obesity. |
fenfluramine
Pondimin®, Redux® Internal medicine An adrenergic appetite suppressing–anorectic amphetamine congener, which, unlike amphetamine, depresses the CNS; fenfluramine ↑ serotonin levels and
imparts a sensation of fullness from a lower intake of food and was prescribed as a short-term adjunct in obesity; it was withdrawn from the market following its association with heart valve abnormalities and other cardiac complications Adverse
effects Pulmonary HTN, attributed either to serotonic vasoconstriction or altered depolarization of pulmonary vascular smooth muscle membrane. See Fen/Phen.
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