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fatty liver of pregnancy

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fatty liver of pregnancy
Acute fatty liver of pregnancy A rare idiopathic complication of pregnancy, most often affecting primiparas with ♂ infants or twins, ± associated with pre-eclampsia Clinical Onset after 35th wk–occasionally by the 13th wk–caveat medicus, possibly progressing to fulminant hepatic failure with jaundice, encephalopathy, DIC, death Management Terminate pregnancy Prognosis ±20% death. See MTP complex.


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Specifically, women who are heterozygote carriers for [beta]-oxidation disorders, particularly long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency, (43) are at risk for preeclampsia and acute fatty liver of pregnancy.
Thrombocytopenia and microangiopathic hemolytic anemia are more severe in HELLP syndrome than in preeclampsia, and acute fatty liver of pregnancy manifests itself primarily as severe liver damage.
 
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