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fasting specimen

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fasting specimen
Lab medicine A blood specimen drawn from a Pt who has not eaten for 12 hrs; fasting is an absolute requirement for a limited number of tests–eg, GTT; prolonged fasting causes a marked–240% ↑ in bilirubin, ↑ plasma TGs, glycerol and free fatty acids, and a marked–± 50% ↓ in glucose. See Glucose tolerance test.


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Fasting specimens must be collected after a 10- to 12-hour complete dietary restriction of everything except water and medications.
A basal-state lipid profile fasting specimen determined by fasting overnight for nine to 12 hours is recommended for collection of a specimen for measurement of the lipid profile of total cholesterol, triglyceride, and HDL cholesterol, mainly because of the highly variable triglyceride diurnal variation.
However, with the positive association found in studies evaluating homocysteine as a CHD risk factor, new methods such as immunoassays have been developed that are more useful in a routine clinical chemistry laboratory,[110,111] Regardless of the method, a fasting specimen should be collected in EDTA or heparin, and the plasma should be removed and analyzed immediately or stored at -70 [degrees] C, where it is stable for extended periods of time.
 
 
 
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