fardel


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far·del

(far'del),
The total measurable penalty that is incurred as a result of the occurrence of a genetic disease in one individual; one of two major quantitative considerations in the prognostic aspects of genetic counseling, the other being risk of occurrence. The fardel roughly measures the duration and the severity of the penalty, that is, the integral of the total time-intensity function; for example, color blindness has a low intensity of penalty throughout life, anencephaly causes intense distress for a brief time, Alzheimer disease is intermediate in both respects but the fardel is greater.
[M.E., fr. O. Fr., fr. Ar. fardah, bundle]

far·del

(fahr'del)
The total measurable penalty that is incurred as a result of the occurrence of a genetic disease in one individual; one of two major quantitative considerations in the prognostic aspects of genetic counseling, the other being risk of occurrence.
[M.E., fr. O. Fr., fr. Ar. fardah, bundle]
References in periodicals archive ?
El corresponsal se queja de que un fardel se deterioro y que se habria de quedar un mulo como reparacion del dano infligido.
Crean, amigos, que para un viejo son fardel muy pesado las obligaciones de la Presidencia.
Lemarie A, Bourdonnay E, Morzadec C, Fardel O, Vernhet L.
Lemarie A, Lagadic-Gossmann D, Morzadec C, Allain N, Fardel O, Vernhet L.
Who would fardels bear", muses the indecisive Shakespearean hero, "To grunt and sweat under a weary life, /But that the dread of something after death,/The undiscovered country, from whose bourn/No traveller returns, puzzles the will,/And makes us rather bear those ills we have/Than fly to others that we know not of?
Who would fardels bear, To grunt and sweat under a weary life, But that the dread of something after death, The undiscovered country, from whose bourn No traveler returns, puzzles the will, And makes us rather bear those ills we have Than fly to others that we know not of?