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familial periodic fever

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familial periodic fever,
a rare autosomal-dominant syndrome that includes an abnormality on the cell receptor for tumor necrosis factor, characterized by periodic fever with any of various skin disorders lasting for 4 days to 3 weeks and mild systemic manifestations, such as abdominal pain, headache, and chest pain. Also called tumor necrosis factor receptor-associated periodic syndrome (TRAPS) .

familial [fah-mil´e-al]
occurring in or affecting members of a family more than would be expected by chance.
familial Mediterranean fever a hereditary disease usually occurring in Armenians and Sephardic Jews, and marked by short recurrent attacks of fever with pain in the abdomen, chest, or joints, and erythema resembling that seen in erysipelas; it is sometimes complicated by amyloidosis.
familial periodic fever a rare autosomal dominant syndrome that includes an abnormality on the cell receptor for tumor necrosis factor; characteristics include periodic fever with any of various skin disorders lasting for four days to three weeks, as well as mild systemic manifestations such as abdominal pain, headache, and chest pain. Called also tumor necrosis factor receptor–associated periodic syndrome.


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