multiple endocrine neoplasia

(redirected from familial multiple endocrine adenomatosis)
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neoplasia

 [ne″o-pla´zhah]
the formation of a neoplasm.
cervical intraepithelial neoplasia (CIN) dysplasia of the cervical epithelium, often premalignant, characterized by various degrees of hyperplasia, abnormal keratinization, and the presence of condylomata.
multiple endocrine neoplasia (MEN) a group of rare hereditary disorders of autonomous hyperfunction of more than one endocrine gland. In Type I (MEN I), called also Wermer's syndrome, there are tumors of the pituitary, parathyroid gland, and pancreatic islet cells in association with a high incidence of peptic ulcer. Type II (MEN II), called also Sipple's syndrome, is characterized by medullary carcinoma of the thyroid, pheochromocytoma, often bilateral and multiple, and parathyroid hyperplasia. Type III (MEN III), called also mucosal neuroma syndrome, resembles Type II except that parathyroid hyperplasia is rare, the mean survival time is shorter, and there may be neuromas and neurofibromas. All forms are transmitted as autosomal dominant traits.

multiple endocrine neoplasia (MEN),

a group of disorders characterized by functioning tumors in more than one endocrine gland.

multiple endocrine neoplasia (MEN)

a hereditary hormonal disorder that occurs in an autosomal-dominant pattern. The endocrine neoplasms may be expressed as hyperplasia, adenoma, or carcinoma and may develop synchronously or metachronously. Some kinds are multiple mucosal neuroma syndrome, Sipple's syndrome, and Werner's syndrome. See also multiple endocrine neoplasia, type I, and multiple endocrine neoplasia, type II.

multiple endocrine neoplasia, type I

a type of multiple endocrine neoplasia that includes tumors of the pituitary, parathyroid glands, and pancreatic islet cells, often with peptic ulcers and sometimes the Zollinger-Ellison syndrome. See also multiple endocrine neoplasia.

multiple endocrine neoplasia, type II

a type of multiple endocrine neoplasia characterized by medullary carcinoma of the thyroid, pheochromocytoma, and hyperplasia of the parathyroid glands. See also multiple endocrine neoplasia.

multiple endocrine neoplasia

See MEN.

mul·ti·ple en·do·crine ne·o·pla·si·a

(MEN) (mŭlti-pĕl endō-krin nēō-plāzē-ă)
A group of disorders characterized by functioning tumors in more than one endocrine gland.

Multiple endocrine neoplasia

Abnormal tissue growth on one or more of the endocrine (hormone-secreting) glands.

mul·ti·ple en·do·crine ne·o·pla·si·a

(MEN) (mŭlti-pĕl endō-krin nēō-plāzē-ă)
Group of disorders characterized by functioning tumors in more than one endocrine gland.
References in periodicals archive ?
It is sometimes called familial multiple endocrine adenomatosis or Wermer's syndrome, after one of the first doctors to recognize it.
It is sometimes called familial multiple endocrine adenomatosis type 1 or Wermer syndrome, after one of the first doctors to recognize it.

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