familial malignancy

familial malignancy

The development of a malignancy in 2+ or more blood-related members of a cohort–eg, hepatocellular carcinoma. See Family cancer syndrome.

Patient discussion about familial malignancy

Q. is cancer genetic? if one in the family has/had cancer does it reflects on the other family member's chances?

A. Unfortunately yes… some types of cancer have a clear genetic tendency, that means that if your mother had breast cancer- your chances to having it too is 10% bigger then anyone else. this is why if you know there’s a cancer tendency in your family, you should take even more care then others. Lower risks, get checked more often…that kind of things.

Q. Can cancer skip every other generation in your family? Can cancer be so hereditary as to skip every other generation in a family? On my dad's side of the family it seems like it does. Both my great grandmothers on my father's side had cancer (breast cancer and another type) and a great grandfather had cancer as well. My grandparents did not have cancer. My father ended up having cancer out of the three of my grandparents’ children. Me nor any of my cousins have had cancer. Is it possible any of our children will?

A. If there is a BRCA mutation, it does not skip generations. A child of a person with a BRCA mutation has a 50/50 chance of having the mutation. Those who have the mutation can pass it on. Those who do not have the mutation cannot pass it on.

Q. ) Hello everyone…..breast cancer is genetic to my family as my mom had one surgery. Hello everyone…..breast cancer is genetic to my family as my mom had one surgery. I know I am also on the risk but I am having migraine and I have been told that this reduces the impact of breast cancer….how come? Any clues?

A. You may not have inherited it from your mother. Your father's DNA matters just as much.

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