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familial hypertrophic cardiomyopathy

   Also found in: Acronyms 0.03 sec.
familial hypertrophic cardiomyopathy
n.
An inherited, often fatal, heart condition caused by a genetic defect affecting production of myosin.

familial hypertrophic cardiomyopathy
An uncommon disease that is a common form of obstructive cardiomyopathy Clinical Angina, arrhythmia, dyspnea, syncope, possibly, sudden death by young adulthood Diagnosis EKG–asymmetric hypertrophy of the septum–usually of left side, systolic anterior movement of mitral valve, and midsystolic closure of aortic valve


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Familial hypertrophic cardiomyopathy and atrial fibrillation caused by Arg663His beta-cardiac myosin heavy chain mutation.
Conclusions On the basis of our findings, it seems that in patients with familial hypertrophic cardiomyopathy who are obese, weight loss can have significant beneficial anatomic and physiologic effects that result in improved cardiac contractility, reduction in cardiac hypertrophy, and reduction in myocardial oxygen demand.
 
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